Management of skin graft donor site in pediatric patients with tumescent technique and AQUACEL<sup>®</sup> Ag foam dressing

Shahzad, Farooq

doi:10.1080/2000656x.2021.1883632

Journal of Plastic Surgery and Hand Surgery

2021

DOI: 10.1080/2000656x.2021.1883632

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Management of skin graft donor site in pediatric patients with tumescent technique and AQUACEL^® Ag foam dressing

Farooq Shahzad

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2024

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Cited by 2 publications

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Recent Updates on the Management of Split-thickness Skin Graft Donor Sites

Markel,

Franke,

Woodberry

et al. 2024

Plastic and Reconstructive Surgery - Global Open

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Background: This article is a narrative review of split-thickness skin graft donor site (STSG-DS) management since the international guidelines were created in 2018. Although many new interventions have been developed, there is a lack of quality, multicentered clinical trials to produce updated evidence-based recommendations. Methods: Electronic databases, including Google Scholar, Web of Science, Medline, and PubMed, were searched by two independent researchers for literature regarding STSG-DS management published from 2018 through 2022, using specific terms in the text, title, and abstract. The primary endpoint assessed was STSG-DS healing, as measured by wound epithelialization. Results: Thirty-one articles were selected, including three systemic review/meta-analyses, five case series, 14 randomized controlled clinical trials, six observational studies, and three nonrandomized trials. Novel interventions for STSG-DS management included in this article describe applications of human amniotic membranes, acellular dermal matrices, cell suspensions and growth factors, biomaterials, electromagnetic radiation, and natural products. Conclusion: Various interventions have shown promise for STSG-DS management since the creation of the 2018 international guidelines; however, studies with more standardized protocols and endpoints are needed to produce up-to-date, evidence-based recommendations and improve outcomes for patients undergoing split-thickness skin grafting.

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Recent Updates on the Management of Split-thickness Skin Graft Donor Sites

Markel,

Franke,

Woodberry

et al. 2024

Plastic and Reconstructive Surgery - Global Open

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Investigation of the Properties of Linen Fibers and Dressings

Gębarowski

Jęśkowiak

Wiatrak

2022

IJMS

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In antiquity, flax was used as a dressing for healing wounds. Currently, work is underway on the genetic modification of flax fibers to improve their properties. Genetic modifications have resulted in an increased content of antioxidants and more favorable mechanical properties. The works published so far have presented independent tests of fibers and dressings after appropriate technological treatments in cell cultures. This study aimed to compare the properties of the fibers and the dressing produced in cell cultures—hamster fibroblasts—V79. The research material was traditional NIKE fibers; genetically modified M, B, and MB fibers; and linen dressings obtained from these fibers. The extract from 48-h incubation of 40 mg of fiber in the culture medium, which was desolved into 10, 20, and 30 mg, was administered to the cell culture. On the other hand, a linen dressing was placed on cells with an area of 0.5 cm2, 1 cm2, 1.5 cm2, and 2 cm2. Cells with fiber or dressing were incubated for 48 h, and then, biological tests were performed, including cell viability (in propidium iodide staining), cell proliferation (in the SRB assay), evaluation of the intracellular free radical level (in the DCF-DA assay), genotoxicity (in the comet assay), assessment of the apoptotic and necrotic cells (in staining anexin-V and iodide propidium), the course of the cell cycle, and the scratch test. The correlation between apoptosis and genotoxicity and the levels of free radicals and genotoxicity were determined for the tested linen fibers and fabrics. The tests presented that the fibers are characterized by the ability to eliminate damaged cells in the elimination phase. However, the obtained fabrics gain different properties during the technological processing of the fibers into linen dressings. Linen fabrics have better regenerative properties for cells than fibers. The linseed dressing made of MB fiber has the most favorable regenerative properties.

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Management of skin graft donor site in pediatric patients with tumescent technique and AQUACEL^® Ag foam dressing

Cited by 2 publications

References 19 publications

Recent Updates on the Management of Split-thickness Skin Graft Donor Sites

Recent Updates on the Management of Split-thickness Skin Graft Donor Sites

Investigation of the Properties of Linen Fibers and Dressings

Contact Info

Product

Resources

About

Management of skin graft donor site in pediatric patients with tumescent technique and AQUACEL® Ag foam dressing

Cited by 2 publications

References 19 publications

Recent Updates on the Management of Split-thickness Skin Graft Donor Sites

Recent Updates on the Management of Split-thickness Skin Graft Donor Sites

Investigation of the Properties of Linen Fibers and Dressings

Contact Info

Product

Resources

About

Management of skin graft donor site in pediatric patients with tumescent technique and AQUACEL^® Ag foam dressing