Management of Soft Tissue Sarcoma

Abstract

Soft tissue sarcomas are a diverse category of rare malignant tumors that originate from mesenchymal tissues, such as muscles, nerves, and adipose tissues. They exhibit substantial morbidity and mortality due to the frequent development of advanced and metastatic conditions. Several challenges have been reported in diagnosis and treatment, with a shift toward molecular characterization and subtyping. Targeted therapy for certain forms of soft tissue sarcomas has seen significant advancements in the previous two decades. Many novel therapeutic strategies have been developed and approved as a result of the ability to study these molecular markers linked to the genesis of sarcomas. An overview of soft tissue sarcoma diagnosis and treatment is given in this chapter.