epinephrine 0.04 µg/kg/min to 0.08 µg/kg/min) and adequate filling. The coronary arteries were inspected by the surgeon to rule out any pressure by the band. Such an occurrence was possible because the great vessels were lying side by side. The ST Segment changes persisted into the postoperative period despite nitroglycerine infusion at 0.5 µg/kg/min and relatively normal arterial oxygen saturations [ Table 1]. After 48 hours, the ST changes subsided without any further intervention.The second case was also a month old baby weighing 2.9 kg, with multiple muscular and inlet VSD with an outlet extension. There was mild hypoplasia of the left atrium and LV. A small Patent Foramen Ovale (PFO) was present. The prebanding saturation was 100%. The banding perimeter was 22 mm at a 0.5 FiO 2 . The PA pressure was 40/17 mmHg with systemic pressures of 80/34 mmHg and systemic oxygen saturations of 82% in the period immediate after banding.In this case too, ST depression of −3 mm was noted without any hemodynamic instability. However, after 10 minutes, tachycardia and worsening of ST depression to −7 mm warranted a loosening of the band to 23 mm. The ST depression reduced to −3 mm in the leads II, III, and AVF but remained at that level despite our attempts to increase the aortic diastolic pressures with blood transfusion and increasing the ionotropic support (epinephrine from 0.02 µg/kg/min to 0.04 µ/kg/min). Similar to the previous case, coronary artery compression by the band was ruled out. The ST depression in this case persisted till the second postoperative day Pulmonary artery banding (PAB) is a useful palliative procedure for a diverse group of patients with congenital cardiac anomalies and unrestricted pulmonary blood flow. With improved results following primary repair of intracardiac anomalies in neonates and infants, PAB is reserved for severely ill patients with complex lesions not amenable to early definitive correction. Currently, PAB is indicated in patients with excessive pulmonary blood flow (PBF) associated with single ventricle (SV) or biventricular physiology. [1] Children undergoing PAB have a stormy postoperative period secondary to sudden alterations in their existing physiology. We noted two neonates who had ST segment changes in the perioperative period, for which we did not have an explanation.The first case is of a month-old baby weighing 2.5 kg diagnosed to have hypoplastic left ventricle (LV), atretic mitral valve, transposed, side by side great arteries, and the SV of right ventricle morphology. There was torrential PBF through an unrestrictive bulboventricular foramen. The baby was taken up for elective atrial septectomy and PAB. The prebanding saturation was 96%. Banding perimeter was 25 mm with a band gradient of 20 mmHg at inspired oxygen fraction of 0.5. Pulmonary artery (PA) pressures were 40/20 mmHg with the systemic pressures of 60/20 mmHg. The patient maintained a saturation of 85% postbanding. Soon after the PA band was tightened, we noticed the appearance of ST depression in the all ...