Management of Vaginal Cancer

Shrivastava, Sushruta; Agrawal, Gaurav; Mittal, Megha; Mishra, Prakash Kumar

doi:10.2174/1574887110666150923112958

Cited by 28 publications

(22 citation statements)

References 32 publications

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“…5 Because it is a very rare condition, we consider it important to report this case of vaginal adenocarcinoma, especially when considering its rapid progression. 1,2,4 In this case, there was no report of patient exposure to DES. 6 As observed by other investigators, this is a young age for non-DES-associated adenocarcinoma.…”

Section: Introductionmentioning

confidence: 80%

“…6 As observed by other investigators, this is a young age for non-DES-associated adenocarcinoma. 1,2,4 In this case, there was no report of patient exposure to DES. Most of the reported cases are of adenocarcinoma, mainly of the intestinal type, that may or may not be associated with in utero DES use.…”

Section: Introductionmentioning

confidence: 80%

“…1 Most cases of vaginal cancer are actually metastases from another primary site, especially the cervix/endometrium or ovary, colon, breast, or pancreas. 1 Most cases of vaginal cancer are actually metastases from another primary site, especially the cervix/endometrium or ovary, colon, breast, or pancreas.…”

Section: Introductionmentioning

confidence: 99%

“…In such cases, it is important to confirm that there is no history of cervical or vulvar carcinoma within the past five years. 1 Most cases of vaginal cancer are actually metastases from another primary site, especially the cervix/endometrium or ovary, colon, breast, or pancreas. 2 In a retrospective study done by Nomura et al, which aimed to identify nonsquamous cell vaginal carcinoma between 1990 and 2013 in Tokyo (Japan), 12 cases (five clear cell carcinoma, three adenocarcinoma, two adenosquamous carcinoma, one carcinosarcoma, and one mucinous adenocarcinoma) were found.…”

Section: Introductionmentioning

confidence: 99%

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Poorly differentiated vaginal adenocarcinoma with aggressive behavior—Pap smear findings

Eleutério

Freitas²,

Oliveira

et al. 2017

Diagnostic Cytopathology

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Vaginal carcinoma is a rare condition. In this report, we describe a case of a poorly differentiated aggressive adenocarcinoma in a woman with a three month history of vaginal bleeding and a negative Pap smear done six months prior to her consultation. Specular examination showed a normal cervix, but there was a bleeding ulcer (2 cm in diameter) in the upper third of the vagina. Cytology revealed poorly differentiated atypical cells, and the biopsy established a diagnosis of vaginal adenocarcinoma with little differentiation. Within two months, the patient died without diagnosis of a primary tumor site other than the vagina.

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Section: Introductionmentioning

confidence: 80%

Section: Introductionmentioning

confidence: 80%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Poorly differentiated vaginal adenocarcinoma with aggressive behavior—Pap smear findings

Eleutério

Freitas²,

Oliveira

et al. 2017

Diagnostic Cytopathology

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“…Local regional recurrence rates for low- and high-risk groups were reported to be 31.2 and 3.2%, respectively [7]. LVSI was found to be a significant factor by univariate regression analysis in a study evaluating risk factors for local recurrence [8].…”

Section: Discussionmentioning

confidence: 99%

Management of Isolated Vaginal Metastasis in Squamous Cell Cervical Cancer: 23 Years' Experience at a Single Center

Güngördük¹,

Kocaer²,

Gülseren³

et al. 2016

Oncol Res Treat

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Aim: The aim of this study was to investigate the treatment options and survival of cervical cancer (CC) patients who develop isolated vaginal metastasis (IVM), and to establish risk factors for IVM. Patients and Methods: A total of 21 cases with IVM were evaluated retrospectively. In addition, 42 control patients diagnosed with CC without recurrence were matched. Tumor size, depth of stromal invasion (DOI), lymphovascular space invasion (LVSI), and size of vaginal and lymph node metastases were analyzed in accordance with the pathology reports. Patients who had IVM were investigated in terms of treatment options (chemotherapy (CT), radiotherapy (RT), or chemoradiotherapy (CRT)) and survival. Results: After detection of IVM, the 1-, 3-, and 5-year survival rates were 57.1, 23.8, and 9.5%, respectively. The mean survival time after metastasis detection was 23.1 ± 31.3 months. LVSI, DOI ≥ 1/2, hemoglobin < 12 g/dl, postmenopausal status, and tumor size ≥ 4 cm were independent risk factors for IVM. The 5-year survival rates were 30.0% for patients receiving RT, 17.1% for patients receiving CRT, and 0% for patients receiving CT. Conclusion: IVM typically develops within the first 2 years after the diagnosis of CC, and survival is generally poor. RT was the most effective treatment in patients with IVM.

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Malignant Disease of the Vulva and the Vagina

Luesley

2018

Dewhurst's Textbook of Obstetrics &Amp; Gynaecology

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Management of Vaginal Cancer

Cited by 28 publications

References 32 publications

Poorly differentiated vaginal adenocarcinoma with aggressive behavior—Pap smear findings

Poorly differentiated vaginal adenocarcinoma with aggressive behavior—Pap smear findings

Management of Isolated Vaginal Metastasis in Squamous Cell Cervical Cancer: 23 Years' Experience at a Single Center

Malignant Disease of the Vulva and the Vagina

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