Geologic carbon sequestration (GCS) is the injection of carbon dioxide (CO2), typically captured from stationary emission sources, into deep geologic formations to prevent its entry into the atmosphere. Active pilot facilities run by regional United States (US) carbon sequestration partnerships inject on the order of one million metric tonnes (mt) CO2 annually while the US electric power sector emits over 2000 million mt--CO2 annually. GCS is likely to play an increasing role in US carbon mitigation initiatives, but scaling up GCS poses several challenges. Injecting CO2 into sedimentary basins raises fluid pressure in the pore space, which is typically already occupied by naturally occurring, or native, brine. The resulting elevated pore pressures increase the likelihood of induced seismicity, of brine or CO2 escaping into potable groundwater resources, and of CO2 escaping into the atmosphere. Brine extraction is one method for pressure management, in which brine in the injection formation is brought to the surface through extraction wells. Removal of the brine makes room for the CO2 and decreases pressurization. Although the technology required for brine extraction is mature, this form of pressure management will only be applicable if there are cost--effective and sustainable methods of disposing of the extracted brine.Brine extraction, treatment, and disposal may increase the already substantial capital, energy, and water demands of Carbon dioxide Capture and Sequestration (CCS). But, regionally specific brine management strategies may be able to treat the extracted water as a source of revenue, energy, and water to subsidize CCS costs, while minimizing environmental impacts. By this approach, value from the extracted water would be recovered before disposing of any resulting byproducts. Until a price is placed on carbon, we expect that utilities and other CO2 sources will be reluctant to invest in capital intensive, high risk GCS projects; early technical, economic, and environmental assessments of brine management are extremely valuable for determining the potential role of GCS in the US.We performed a first order feasibility and economic assessment, at three different locations in the US, of twelve GCS extracted--water management options, including: geothermal energy extraction, desalination, salt and mineral harvesting, rare--earth element harvesting, aquaculture, algae biodiesel production, road de--icing, enhanced geothermal system (EGS) recharge, underground reinjection, landfill disposal, ocean disposal, and evaporation pond disposal. Three saline aquifers from different regions of the US were selected as hypothetical GCS project sites to encompass variation in parameters that are relevant to the feasibility and economics of brine disposal. The three aquifers are the southern Mt. Simon Sandstone Formation in the Illinois Basin, IL; the Vedder Formation in the southern San Joaquin Basin, CA; and the Jasper Interval in the 3 eastern Texas Gulf Basin, TX. These aquifers are candidates for GCS due ...