In Ayurvedic classics, Sandhigatavata is among eighty Nanatmaja Vata Vyadhi. As age advances, Vata Dosha
increases in an individual. This increasing Vata accelerates Dhatu Kshaya (depletion of tissues) and Bala Kshaya
(reduction of strength). Sandhigata Vata is a common disorder that occurs due to Dhatukshya. Sandhigatavata is
the most common joint disorder worldwide. Shoola is the cardinal feature associated with Sandhishotha with
Vatapurnadrutisparsha of this disease. If the condition manifests in Janusandhi, then it is called Janu Sandhigata
Vata. Janusandhigatavata is also correlated to Knee osteoarthritis due to the resemblance in signs and symptoms,
i.e., joint pain, stiffness, muscle weakness, swelling of the knee joint, deformed joint, reduced range of motion
and loss of use of the joints and cracking sounds and progressive softening and disintegration of articular cartilage
accompanied by the growth of osteophytes. The knee joint is weight-bearing, the strongest and most important
joint in the body. Movements at the knee joint are essential for all everyday activities, including walking, running,
sitting, and standing. Different modalities of treatment have been explained in the Ayurvedic classics to treat this
disease. Here, an attempt has been made via Janubasti with Ksheerbala taila and Shallaki as Shamana Aushadhi.
A patient XYZ of age 60years was treated with an External Panchakarma procedure, i.e., Janubasti with Ksheerbala taila for 12 days continuously, and oral medication was Shallaki started from the 1st
day to the 12th day. Follow-up was done for 24 days to see improvement, and the patient got significant improvement in the sign and
symptoms of the disease.