Managing Asthma and Obesity Related Symptoms (MATADORS): An mHealth Intervention to Facilitate Symptom Self-Management among Youth

Nichols, Michelle; Teufel, Ronald J.; Miller, Sarah; Madisetti, Mohan; Giovanni, Christine San; Chike-Harris, Katherine; Jones, Lacy; Prentice, Margaret; Ruggiero, Kenneth J.; Kelechi, Teresa J.

doi:10.3390/ijerph17217750

Cited by 13 publications

(13 citation statements)

References 51 publications

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“…We anticipate that these results will substantiate the need for targeted care for high-risk asthma patients. Thus, these findings and the knowledge of ED in asthma may have important implications for therapeutic strategies, as severe refractory asthma is a serious problem with high morbidity and mortality in patients and a significant economic burden on healthcare [ 32 ]. Moreover, Makieieva et al reported the dependence of asthma severity on the functional state of the vascular endothelium [ 3 ].…”

Section: Discussionmentioning

confidence: 99%

Bronchial Asthma as a Cardiovascular Risk Factor: A Prospective Observational Study

et al. 2022

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Introduction: Asthma as a chronic inflammatory disorder has been suggested as a risk factor for endothelial dysfunction (ED), but studies on the association between asthma and cardiovascular disease (CVD) risk are limited. Background: We assessed associations of ED with the severity of asthma, eosinophilic inflammation, lung function, and asthma control. Methods: 52 young asthmatics (median age of 25.22 years) and 45 healthy individuals were included. Demographic, clinical, and laboratory findings were recorded. We evaluated microvascular responsiveness by recording the reactive hyperemia index (RHI) indicating post-occlusive peripheral endothelium-dependent changes in vascular tone using the Itamar Medical EndoPAT2000. VCAM-1, ADMA, high-sensitive CRP (hsCRP), and E-selectin were measured. Results: Asthmatics had considerably lower RHI values (p < 0.001) with a dynamic decreasing trend by asthma severity and higher hsCRP levels (p < 0.001). A substantial increase in hsCRP and E-selectin with asthma severity (p < 0.05) was also observed. We confirmed a higher body mass index (BMI) in asthmatics (p < 0.001), especially in women and in severe asthma. Conclusions: We demonstrated the progression of CVD in asthmatics and the association of the ongoing deterioration of ED with the inflammatory severity, suggesting that the increased risk of CVD in young asthmatics is dependent on disease severity. The underlying mechanisms of risk factors for CVD and disease control require further study.

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Section: Discussionmentioning

confidence: 99%

Bronchial Asthma as a Cardiovascular Risk Factor: A Prospective Observational Study

et al. 2022

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“…Overall, 74% (56/76) of these interventions were mobile based, especially in the last few years. Future studies will focus on a variety of digital interventions, often combining different monitoring tools, such as a diary, lung function measurements, medication adherence, and ACT scores [ 117 , 152 , 197 , 209 , 213 , 285 , 286 ], with a trend toward more automatization in remote monitoring [ 117 , 209 , 213 ].…”

Section: Resultsmentioning

confidence: 99%

eHealth Technologies for Monitoring Pediatric Asthma at Home: Scoping Review

Kamp¹,

Hengeveld²,

Brusse-Keizer³

et al. 2023

J Med Internet Res

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Background eHealth monitoring technologies offer opportunities to more objectively assess symptoms when they appear in daily life. Asthma is the most common chronic disease in childhood with an episodic course, requiring close follow-up of pediatric asthma control to identify disease deterioration, prevent exacerbations, and enhance quality of life. eHealth technologies in pediatric asthma care show promising results regarding feasibility, acceptability, and asthma-related health outcomes. However, broad systematic evaluations of eHealth technologies in pediatric asthma are lacking. Objective The objective of this scoping review was to identify the types and applications of eHealth technologies for monitoring and treatment in pediatric asthma and explore which monitoring domains show the most relevance or potential for future research. Methods A scoping review was conducted using the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines. A systematic and comprehensive search was performed on English papers that investigated the development, validation, or application of eHealth technologies for home monitoring or treatment of pediatric asthma in the following databases: PubMed, Cochrane Library, IEEE, Scopus, CINAHL, PsycINFO, and ACM Digital Library. Two authors independently assessed eligibility and extracted data. Data were presented by a descriptive analysis of characteristics and a narrative report for each eHealth domain. Results The review included 370 manuscripts. The following 10 monitoring domains were identified: air quality, airway inflammation markers, lung function, physical activity, sleep, audiovisual, other physiological measurements, questionnaires, medication monitoring, and digital environment (ie, digital platforms, applications, websites, and software tools to monitor or support monitoring). Rising numbers of studies were seen, and the numbers accelerated in the last few years throughout most domains, especially medication monitoring and digital environment. Limited studies (35/370, 9.5%) of multiparameter monitoring strategies, using three or more domains, were found. The number of monitoring validation studies remained stable, while development and intervention studies increased. Intervention outcomes seemed to indicate the noninferiority and potential superiority of eHealth monitoring in pediatric asthma. Conclusions This systematic scoping review provides a unique overview of eHealth pediatric asthma monitoring studies, and it revealed that eHealth research takes place throughout different monitoring domains using different approaches. The outcomes of the review showed the potency for efficacy of most monitoring domains (especially the domains of medication monitoring, lung function, and digital environment). Future studies could focus on modifying potentially relevant hospital-based diagnostics for the home setting to investigate potential beneficial effects and focus on combining home-monitoring domains to facilitate multiparameter decision-making and personalized clinical decision support.

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“…Currently, most mHealth apps developed for pediatric patient populations have focused on symptom monitoring and self-management for a wide range of chronic illnesses (Nichols et al, 2020). A symptom monitoring app for children undergoing HCT, TRU-PBMT, was well-liked and utilized by participants on more than half of the days studied (Vaughn et al, 2020(Vaughn et al, , 2021.…”

Section: Discussionmentioning

confidence: 99%

Usability and Acceptability of the QuestLeukemia Mobile Application: A Pilot Study for An Educational and Psychological Intervention for Children with Chronic Illnesses

Meyer

Wang

Yearley

et al. 2022

Journal of Pediatric Hematology/Oncology Nursing

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It is widely accepted that educational interventions benefit children with chronic diseases (disease awareness and autonomy) or those undergoing medical procedures (decreased anxiety and improved satisfaction). Hematopoietic cell transplantation (HCT) is an intensive procedure to treat life-threatening diseases but is associated with multiple adverse medical experiences. QuestLeukemia (QuestED, Durham, NC) is a mobile app designed to educate pediatric patients preparing for HCT through age-appropriate videos and quizzes. Here we describe the results of the initial pilot study assessing acceptability and feasibility of QuestLeukemia app. Eligible participants were selected from a convenience sample (inpatient HCT unit and outpatient clinic). Participants spent 30–60 min using the app then completed a survey assessing the app for usability, accessibility, and user satisfaction. Participants identified the app as a useful tool for gaining disease-related knowledge and reported greater autonomy over their disease process. On average, patients indicated that the app was easy to use ( M = 4.93), enjoyable ( M = 4.79), and comprehensive ( M = 4.71). Parents followed similar trends of satisfaction with the app. Pediatric HCT providers likewise reported that the app was easy to use ( M = 4.22), enjoyable ( M = 4.85), and educationally comprehensive ( M = 4.77). The QuestLeukemia mobile application prototype provides an easy, enjoyable, and educational tool for pediatric patients undergoing HCT. This application was well received by patients, parents, and providers. These findings will be used to design future iterations of the game in clinical care.

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Managing Asthma and Obesity Related Symptoms (MATADORS): An mHealth Intervention to Facilitate Symptom Self-Management among Youth

Cited by 13 publications

References 51 publications

Bronchial Asthma as a Cardiovascular Risk Factor: A Prospective Observational Study

Bronchial Asthma as a Cardiovascular Risk Factor: A Prospective Observational Study

eHealth Technologies for Monitoring Pediatric Asthma at Home: Scoping Review

Usability and Acceptability of the QuestLeukemia Mobile Application: A Pilot Study for An Educational and Psychological Intervention for Children with Chronic Illnesses

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