A six weeks long study trial was conducted on Japanese quails to evaluate the growth performance, carcass traits, some blood parameters and oxidative status when different vegetable oils were supplemented through diet. A total of 400, 3 days old, Japanese quails, were randomly divided into four different groups and each consisting of 100 quails. Each of the main group was further divided into five replicates and each replicate was composed of 20 quails. Soybean oil, sunflower oil, safflower oil and olive oil was supplemented to experimental diets separately at level of 3%. The results showed that there were no changes in terms of growth performance and carcass traits as well as alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, total protein, triglyceride and cholesterol levels in all experimental groups with soybean oil, sunflower oil, safflower oil and olive oil supplementation (p>0.05). However it was observed that, the serum malondialdehyde level was decreased, whereas serum antioxidant activity level was significantly increased (p<0.05) in the safflower oil treatment group. From the results, it could be concluded that supplementation of soybean, sunflower, safflower and olive oil in quail diets had neither harmful nor beneficial effects on the growth performance, carcass traits, serum biochemical parameters and oxidation status of breast meat. Furthermore, it can also be stated that prevention of serum lipid oxidation might be more effective by supplementation of safflower oil in quails.