“…ICU delirium has been referred to as ICU psychosis, acute brain dysfunction or failure, and acute encephalopathy, among other terms. ICU delirium can prolong mechanical ventilation and is associated with a threefold higher rate of re-intubation, an increased rate of ventilator-associated infections, prolonged hospital stays, and increased 1-year mortality [290,291]. Delirium is defined as a fluctuating change in attention, cognition, consciousness, and/or perception and can be further categorized as hyperactive, hypoactive, and mixed [290,292].…”