Managing Missing Data in Patient Registries

Mack, Christina; Su, Zhaohui; Weistreich, Daniel

doi:10.23970/ahrqregistriesmissingdata

Cited by 66 publications

(33 citation statements)

References 18 publications

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“…For the current review, the rate of attrition likely increased with the severity of depressive symptoms and therefore data is likely not missing at random [ 38 ]. This presents challenges for analysis as common missing data techniques (e.g., imputation) are not appropriate for data not missing at random but the estimate of the effect may be biased due to the missingness [ 39 ]. This limits the generalizability of the prognostic factors identified to those with more severe depression/depressive symptoms.…”

Section: Discussionmentioning

confidence: 99%

Prognostic factors of depression and depressive symptoms after hip fracture surgery: systematic review

et al. 2021

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Background Patients with hip fracture and depression are less likely to recover functional ability. This review sought to identify prognostic factors of depression or depressive symptoms up to 1 year after hip fracture surgery in adults. This review also sought to describe proposed underlying mechanisms for their association with depression or depressive symptoms. Methods We searched for published (MEDLINE, Embase, PsychInfo, CINAHL and Web of Science Core Collection) and unpublished (OpenGrey, Greynet, BASE, conference proceedings) studies. We did not impose any date, geographical, or language limitations. Screening (Covidence), extraction (Checklist for critical Appraisal and data extraction for systematic Reviews of prediction Modelling Studies, adapted for use with prognostic factors studies Checklist), and quality appraisal (Quality in Prognosis Studies tool) were completed in duplicate. Results were summarised narratively. Results In total, 37 prognostic factors were identified from 12 studies included in this review. The quality of the underlying evidence was poor, with all studies at high risk of bias in at least one domain. Most factors did not have a proposed mechanism for the association. Where factors were investigated by more than one study, the evidence was often conflicting. Conclusion Due to conflicting and low quality of available evidence it is not possible to make clinical recommendations based on factors prognostic of depression or depressive symptoms after hip fracture. Further high-quality research investigating prognostic factors is warranted to inform future intervention and/or stratified approaches to care after hip fracture. Trial registration Prospero registration: CRD42019138690.

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Section: Discussionmentioning

confidence: 99%

Prognostic factors of depression and depressive symptoms after hip fracture surgery: systematic review

et al. 2021

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“…Our decision to categorize data as MAR was based on the fact that the data missing was systematically related to the observed but not the unobserved data. We did not find any evidence that data was missing not at random (MNAR) [ 30 ]. For example, we did not find that individuals with lower income were more likely to have missing income data.…”

Section: Methodsmentioning

confidence: 99%

Blocking and being blocked on gay dating apps among MSM attending a sexual health clinic: an observational study

et al. 2021

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Background There are limited studies on blocking and men who have sex with men (MSM) health outcomes. We need such data in China, to better understand the relationship between Chinese MSM gay app use and health outcomes, thus providing insight on risky sexual behaviors and HIV transmission among Chinese MSM - one of the world’s largest MSM communities. Blocking someone is when users select a function on an app to prevent another user from contacting them and being blocked is when someone is prevented from contacting another user. We studied the correlates of blocking on the world’s largest gay dating app among Chinese MSM (N = 208). Methods We conducted a cross-sectional survey as part of an HIV testing intervention in Guangzhou, China, May–December 2019. Using logistic regression models, we estimated the correlates of blocking (e.g. sociodemographic characteristics, sexual behavior, HIV testing history, social network data). Results MSM had a mean age of 27.9 years (SD = 7.1) and median of one sexual partner in the last 3 months. About 62% had blocked someone in their lifetime and 46% had been blocked in their lifetime. Each additional male partner was associated with an 87% (aOR = 1.87, 95%CI = 1.03, 3.40) increased chance of being blocked. Reporting a versatile sexual role was related with a 90% (aOR = 0.10, 95%CI = 0.02, 0.45) decreased likelihood of blocking behavior and an 86% (aOR = 0.14, 95%CI = 0.04, 0.46) reduced chance of being blocked. Conclusions Number of male partners may be associated with blocking behavior, with implications for the design of online sexual health interventions.

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“…In addition to consultation work with autistic adults described above, we assessed the acceptability of the GHQ-12 by examining missingness (Mack et al 2018 ). Systematic patterns of missing data may indicate that some participants were less likely to answer specific questions than others, or that participants consistently avoided particular questions.…”

Section: Methodsmentioning

confidence: 99%

An Assessment of the Psychometric Properties of the GHQ-12 in an English Population of Autistic Adults Without Learning Difficulties

Mayhew

Stuttard

Beresford

2020

J Autism Dev Disord

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Valid and reliable tools to measure mental health are a key requirement to developing a robust evidence base on mental health difficulties and autism. There are several reasons why mental health measures developed for the neurotypical population may not be valid and reliable when used with autistic adults. Using data collected from a national evaluation of community-based, specialist autism provision in England, this study assessed the psychometric properties of the General Health Questionnaire (GHQ-12) in a population of autistic adults without learning difficulties. We examined the measure’s acceptability, reliability and internal construct validity. The GHQ-12 was found to have good psychometric properties in this population. This provides first evidence that this measure can be used with autistic adults without LD.

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Managing Missing Data in Patient Registries

Cited by 66 publications

References 18 publications

Prognostic factors of depression and depressive symptoms after hip fracture surgery: systematic review

Prognostic factors of depression and depressive symptoms after hip fracture surgery: systematic review

Blocking and being blocked on gay dating apps among MSM attending a sexual health clinic: an observational study

An Assessment of the Psychometric Properties of the GHQ-12 in an English Population of Autistic Adults Without Learning Difficulties

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