“…From 2019 to 2020, thousands of residents across Toronto crossed these thresholds due to COVID-19 transit reductions, further tightening patients’ access windows and reducing their resilience to the often unpredictable clinic lines ( Lam et al, 2020 ), as well as transit disruptions. ( Itani et al, 2019 , Liu et al, 2020 ) At almost every travel window, whether weekdays from 8am-9am, 11am-12pm, 3pm-4pm, or Saturday 9am-10am, we estimate that hundreds of potential people using opioids within the city's 5th quintile of material and social deprivation had travel times to treatment cross 30 and 20-minute time thresholds. The third analysis found that residents only faced increases in travel time by over 10 minutes on weekdays (an additional 2.5 hours of travel time weekly).…”