1999
DOI: 10.1136/thx.54.11.972
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Mandibular advancement oral appliance therapy for obstructive sleep apnoea: effect on awake calibre of the velopharynx

Abstract: Background-The mechanisms of action of oral appliance therapy in obstructive sleep apnoea are poorly understood.Videoendoscopy of the upper airway was used during wakefulness to examine whether the changes in pharyngeal dimensions produced by a mandibular advancement oral appliance are related to the improvement in the severity of obstructive sleep apnoea. Methods-Fifteen

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Cited by 206 publications
(157 citation statements)
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“…Computerised tomography has been used to demonstrate that not only an increase in the airway space but also a change in shape accompanies the use of an oral appliance. 12 More recently, Ryan et al, 13 using videofluoroscopy, described increases in cross-sectional area of the upper airway, particularly in the velopharynx, when a MAS was worn.…”
Section: Rationale For the Use Of Mandibular Advancement Splintsmentioning
confidence: 99%
See 1 more Smart Citation
“…Computerised tomography has been used to demonstrate that not only an increase in the airway space but also a change in shape accompanies the use of an oral appliance. 12 More recently, Ryan et al, 13 using videofluoroscopy, described increases in cross-sectional area of the upper airway, particularly in the velopharynx, when a MAS was worn.…”
Section: Rationale For the Use Of Mandibular Advancement Splintsmentioning
confidence: 99%
“…Based on the findings of a review of twenty-one publications, undertaken by the American Sleep Disorders Association, the mean apnoeahypopnoea index (AHI) appeared to reduce from 47 to 19. 13 However, whilst the authors completed a comprehensive review of all available published data on the use of intra-oral appliances for the management of OSA, the review has several limitations:…”
Section: Rationale For the Use Of Mandibular Advancement Splintsmentioning
confidence: 99%
“…2 Oral appliances (OAs), aiming to enlarge the upper airway by repositioning the mandible forward, [3][4][5] as a lifelong treatment. 6,7 Hence, knowledge of side effects and their likely prevalence is important in helping to optimize patient selection and to monitor treatment effects.…”
Section: Introductionmentioning
confidence: 99%
“…32 Mandibular opening has been shown to occlude the oropharyngeal airway in subjects with increased vertical facial proportions and retrognathic mandible. 32 Ryan et al 35 found the lateral diameter of the velopharynx was the airway site that changed the most with mandibular advancement splints. It may be that the nonresponders in this study had obstruction, either high in the nasopharynx or very low in the pharynx beyond the therapeutic range of the splint.…”
Section: Two Of the Most Commonly Used Measures In Assessing Treatmenmentioning
confidence: 99%