Mandibular Central Mucoepidermoid Carcinoma: A Case Report and Review of the Literature

Abstract

We report the case of a patient whose main complaint was swelling on the right side of the mandible when he presented to the Ear, Nose and Throat (ENT) Service. Imaging studies revealed a large homogeneous, multilocular, expansive lesion in the body of the right mandibular ramus. The lesion was poorly enhanced following intravenous contrast injection. The patient was treated with hemimandibular surgical resection, fibula free flap reconstruction and adjuvant radiotherapy. Currently, the patient is disease free and free of posttreatment complications.

Central mucoepidermoid carcinoma radiographically mimicking an odontogenic tumor: A case report and literature review

“…[ 3 5 ] In this case, the provisional diagnosis was ameloblastoma, just as the most common diagnostic hypotheses are tumors and odontogenic cysts as observed in Table 1 . [ 12 13 14 15 16 17 18 19 20 21 22 23 ]…”

High-grade central mucoepidermoid carcinoma arising in an odontogenic cyst: a case report and review of the literature

“…The most common signs and symptoms are: asymmetry caused by intraosseous expansion [3,6,[8][9][10][11][12][15][16][17][18][19][20][21][22][23], pain [3,[8][9][10][11][18][19][20][21][22][23], higher tooth mobility [24], trismus [8,24], and bleeding [23]. The following are less frequently mentioned in the literature [11,22,24]: nasal congestion [17], headaches [17], tinnitus [10,25], loss of hearing [25], or diplopia [20], when it comes to the maxilla. In case of the mandible, high-grade tumors were causing paresthesia along with hypoesthesia of the lower lip and teeth (Vincent symptom) [23,26].…”

Central mucoepidermoid carcinoma of the mandible associated with Systemic lupus erythematosus: Central mucoepidermoid carcinoma

“…Brookstone and Huvos reported recurrence rate of 40% with conservative approaches such as marsupialisation, curettage and enucleation while only 4% recurrence was observed with aggressive treatment such as segmental resection with or without neck dissection and advujant therapy [7]. Neck dissection is done in case of nodal involvement [1,2,4,8].…”

“…Although MEC is considered to be radio resistant, postoperative radiotherapy has been shown to improve loco-regional control [6]. Adjuvant Radiotherapy is recommended in the case of close or positive margins and in intermediate to high grade tumours [1,2,4,[6][7][8][9].…”