Mandibular mass in pediatric patient: A diagnostic dilemma

Abstract

A case of aggressive juvenile ossifying fibroma in a child has been discussed. The unique appearance of this particular lesion demonstrates a close relationship between aggressive ossifying fibroma and well-differentiated osteogenic sarcoma. The age of the patient and the location of the tumor in the case presented made it mandatory to utilize multiple diagnostic parameters and adjunctive diagnostic help to resolve the dilemma posed by this tumor. Differentiation of ossifying fibroma from other benign and malignant neoplasms as well as fibrous dysplasia is important in correct management of the lesion.

Osteoid producing primary lesion at morphologic and biologic interface

“…The histologic test of aggressive ossifying fibroma is dense cellular proliferation of polyhedral and spindle shaped cells arranged in a whorled pattern. Osteoclasts, osteoid are also seen rapidly expanding central jaw lesions of children and adolescents (2,12). Ossifying fibroma appearing as fast growing mass between 5 and 15 yrs of age, radiologically well bordered and consistent with ossifying fibroma histologically are referred to as juvenile ossifying fibroma.…”