Defects requiring reconstruction in the mandible are commonly encountered and may result from resection of benign or malignant lesions, trauma, or osteoradionecrosis. Mandibular defects can be classified according to location and extent, as well as involvement of mucosa, skin, and tongue. Vascularized bone flaps, in general, provide the best functional and aesthetic outcome, with the fibula flap remaining the gold standard for mandible reconstruction. In this review, we discuss classification and approach to reconstruction of mandibular defects. We also elaborate upon four commonly used free osteocutaneous flaps, inclusive of fibula, iliac crest, scapula, and radial forearm. Finally, we discuss indications and use of osseointegrated implants as well as recent advances in mandibular reconstruction. Continuing advances in mandibular reconstruction have greatly improved functional and aesthetic outcomes for patients. Outcomes from free vascularized bone flaps have proved markedly superior to those obtained from use of nonvascularized options such as reconstruction plates and bone grafts. The free fibula flap continues to remain the gold standard for mandibular reconstruction against which other modalities are compared.The mandible serves several important functions in the head and neck, which can be restored to nearnormality with the use of vascularized bone flaps. It provides a stable platform for the oral cavity and also a structure to which muscles attach. Most importantly, it allows mastication by providing a stable counterpoint to the maxilla and serving as a base for attachment of dentition. It facilitates speech, swallowing, and breathing by maintaining space within the oral cavity and allowing the tongue to function. It also serves an aesthetic function, defining the projection of the lower third of the face.
ANATOMY OF THE MANDIBLEThe mandible is a U-shaped bone that articulates with the skull base through two unique temporomandibular joints (TMJs), which allow smooth and coordinated mouth opening. The TMJ is a diarthrodial joint, consisting of two bones articulating in a discontinuous fashion allowing freedom of movement dictated by muscles and limited by ligamentous attachments. The TMJ is also lined on its internal aspect by synovium, which secretes synovial fluid, serving both as a lubricant and a nutrition source for joint structures.