Manejo de la atrofia vulvovaginal posmenopáusica

Monterrosa-Castro, Álvaro; Portela-Buelvas, Katherin

doi:10.4067/s0717-75262014000600006

Cited by 1 publication

(3 citation statements)

References 38 publications

(85 reference statements)

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“…The increase in life expectancy of women necessitates further scientific study and the development of appropriate therapies for the relief of GSM symptoms that can be used for all women [ 20 , 21 , 22 ]. GSM is a factor that impacts the quality of life and affects a broad age group [ 1 , 3 , 4 , 6 ]. Changes resulting from low postmenopausal estrogen levels immensely affect the female genitourinary tract, causing signs and symptoms characteristic of this phase, which tends to worsen over time.…”

Section: Discussionmentioning

confidence: 99%

“…Because of socioeconomic and sociocultural changes, a significant increase in life expectancy has occurred, especially among women. Accordingly, the number of women reaching menopause increases annually [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

“…Menopause is a period of physiological changes that affect various organs and systems, thereby compromising the quality of life for many women [ 1 ]. It is marked by ovarian failure and decreased estrogen production, which can generate physical and neurovegetative symptoms [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Efficacy of Fractional Laser on Steroid Receptors in GSM Patients

Pinho,

Heinke,

Dutra

et al. 2023

Bioengineering

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Background: To compare the efficacy of CO2 fractional laser with that of topical estriol for treating genitourinary syndrome of menopause and to investigate the relationship between epithelial thickness and vaginal atrophy. Methods: Twenty-five menopausal women were randomized to receive either laser or estrogen treatment. Vaginal biopsies before and after treatment were compared to assess the amount and distribution of estrogen and progesterone receptors. Results: Estrogen receptor levels were statistically similar between groups before and after treatment. Although there was no change over time in the estrogen group, an increase in receptor levels was confirmed in the laser group. Changes in estrogen receptor levels showed no association with treatment. Progesterone receptor levels were statistically similar between groups throughout treatment. There was no change over time in both groups. These changes displayed no association with the type of treatment. There was no significant correlation between epithelium thickness and estrogen or progesterone receptor levels. Conclusions: Estrogen and progesterone receptor levels increased and were maintained, respectively, in the vaginal epithelium in both groups. There was no significant relationship between epithelium thickness and receptor density. Laser therapy had similar outcomes to the gold standard without involving the disadvantages of hormone therapy.

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