Manfaat Probiotik dalam Perawatan Kulit : Review

Pratiwi, Elasari Dwi; Susanti, Susanti

doi:10.24198/mfarmasetika.v6i4.35690

Cited by 2 publications

(2 citation statements)

References 33 publications

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“…According to Seite and Misery (2018), there is a relationship between normal skin microflora, skin barrier function, and skin sensitivity, including skin care products that can improve everything. Skin can be influenced by the environment, genetics, diet, and lifestyle (Pratiwi and Susanti, 2021). This imbalance can also be influenced by the presence of external parasites such as mites, fleas, ticks, or fleas because they can also have toxic effects (Guner et al, 2021;Krol et al, 2019).…”

Section: Observation Of Skin Anatomy Pathologymentioning

confidence: 99%

Evaluation of Acute Dermal Toxicity of Hibiscus Leaves as Simplicial Ointment on Albino Rats

Saputra,

Sudira,

Samsuri

et al. 2023

J. Med. Vet.

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Hibiscus is a plant that has been shown to contain substances that may be used as sunscreen to protect the skin from UV radiation. In terms of their potential as sunscreens, flavonoids, tannins, and quinone chemicals are crucial because they are antioxidants that can reduce the negative effects of UV radiation and boost photoprotective activity. This study aimed to investigate the acute dermal toxicity potential of hibiscus leaves simplicial ointment 40% on female albino rats. The evaluation method refered to The OECD Guideline for Testing of Chemicals – No. Test: 402, Acute Dermal Toxicity-Fixed Doses Procedure. Based on the Globally Harmonized System compared to this study reported that acute dermal median lethal dose (LD50) was > 2000 mg/kg. It can be concluded that hibiscus leaves simplicial ointment 40% has safe to apply topically and doesn't produce acute skin toxicity.

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Section: Observation Of Skin Anatomy Pathologymentioning

confidence: 99%

Evaluation of Acute Dermal Toxicity of Hibiscus Leaves as Simplicial Ointment on Albino Rats

Saputra,

Sudira,

Samsuri

et al. 2023

J. Med. Vet.

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“…Probiotics were added to this preparation as a second active ingredient. In recent years, probiotics used as active ingredients in the skincare (Pratiwi & Susanti, 2021;Pratiwi & Susanti, 2023). The cosmetic industry which develops skincare products has recognised the importance of probiotics as "bioactive ingredients" in enhancing the beauty.…”

Section: Introductionmentioning

confidence: 99%

Exploration of probiotics on antioxidant activity of serum NLC coenzyme Q10 using the DPPH (2,2-diphenyl-1-picrylhidrazyl) method

Pratiwi,

Mayangsari,

Susanti

2024

Pharm Educ

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Background: The skin ageing process can be slowed by routinely caring for the skin using serum cosmetics containing antioxidants such as Co-enzyme Q10 (CoQ10). However, CoQ10 has a drawback, which is low penetration into the skin. In this study, an antiaging serum preparation with the active ingredient NLC-CoQ10 was prepared. Probiotics were added to this preparation as a second active ingredient to enhance antioxidant activity. Objective: This study aimed to analyse the effect of probiotic concentration on the physical characteristics and antioxidant activity of NLC-CoQ10 serum. Method: NLC-CoQ10 was mixed with serum base and 0% probiotic (Formula One), 2% probiotic (Formula Two), and 4% probiotic (Formula Three). After that, physical characteristics and antioxidant activity were observed. Results: The results show that the physical characteristics of all formulas fulfil the specifications. All formulas had pH values between 4 and 7 and a viscosity value between 230 and 1150 cPs. The formula with the highest viscosity value is F1, 352.00 ± 2.00. All formulas have statistically different IC50 values. IC50 values for F1, F2 and F3 respectively, are 317.809 ± 2.117; 307.985 ± 2.089; 257.549 ± 1.573. Conclusion: The antioxidant activity increases with increasing concentrations of probiotics in NLC-CoQ10 serum. Meanwhile, the viscosity value decreases with a decreasing concentration of probiotics.

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Manfaat Probiotik dalam Perawatan Kulit : Review

Cited by 2 publications

References 33 publications

Evaluation of Acute Dermal Toxicity of Hibiscus Leaves as Simplicial Ointment on Albino Rats

Evaluation of Acute Dermal Toxicity of Hibiscus Leaves as Simplicial Ointment on Albino Rats

Exploration of probiotics on antioxidant activity of serum NLC coenzyme Q10 using the DPPH (2,2-diphenyl-1-picrylhidrazyl) method

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