“…The literature also documents the concurrent, face, and predictive validity of BPD in childhood (Biederman, et al, 2003). Recent work suggests that pediatric onset BPD may represent a unique developmental type of BPD characterized by a chronic course, mixed presentations, and high levels of severe irritability , Biederman, et al, 2003, Carlson, 1984, Geller, et al, 2006, Geller, et al, 2004, Wozniak, et al, 1995. For instance, two ongoing multisite, National Institute of Mental Health (NIMH) funded studies show that children and adolescents with BPD maintain a functionally impaired status characterized by a highly relapsing and remitting course , Birmaher, 2004, Geller, et al, 2006, Geller, et al, 2004.…”