2013
DOI: 10.1016/j.arbres.2012.11.005
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Manifestaciones pulmonares de las enfermedades del colágeno

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Cited by 18 publications
(3 citation statements)
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“…[ 17 ] Insults to the lungs, including infectious and noninfectious causes, are often associated with an inflammatory process that eventually leads to airway destruction and, consequently, dilation of the bronchial tree. [ 16 19 20 21 22 23 ]…”
Section: Pathogenesismentioning
confidence: 99%
See 1 more Smart Citation
“…[ 17 ] Insults to the lungs, including infectious and noninfectious causes, are often associated with an inflammatory process that eventually leads to airway destruction and, consequently, dilation of the bronchial tree. [ 16 19 20 21 22 23 ]…”
Section: Pathogenesismentioning
confidence: 99%
“…These changes in pulmonary structure build a suitable environment for bacterial colonization and subsequent airway infections. [ 19 20 21 ] The repeated cycles of infection lead to further airway damage and the vicious cycle continues. Bronchiectasis is characterized by irreversibly dilated and abnormally thickened bronchial walls.…”
Section: Pathogenesismentioning
confidence: 99%
“…Starting from the first culprit step of the process-persistent or recurrent infection-we can identify two main etiological groups: (1) childhood infections, including persistent bacterial bronchitis (PBB) [11], pneumonia, measles, whooping cough and tuberculosis; and (2) adult infections, including non-tuberculous mycobacteria (NTM) infections [12]. Instead, progressive inflammation is the main pathophysiological determinant in other two etiological groups of NCFB: (1) toxic damage to airways, as in case of inhalation, aspiration secondary to neuromuscular diseases and gastro-oesophageal reflux disease (GERD), and (2) systemic inflammatory diseases, including inflammatory bowel disease [13], connective tissue diseases [14] and yellow nail syndrome [15]. In contrast, defects in the immune system are responsible of another etiological group of NCFB including primary and secondary immune deficiencies.…”
Section: Introductionmentioning
confidence: 99%