Increases in human population and per-capita consumption are putting enormous pressure on land resources. About 38% of the Earth's land area is being used in agricultural production [1], with about half (ca. 31%) of the remaining land being under forest cover [2] and the other half being less suitable for agricultural production due to edaphic, topographic and/or climatic factors. Despite the fact that over the last three decades the world food production has doubled [3], about 1 in 9 people in the world is still undernourished [4]. This poses the global challenge of increasing food security without exacerbating serious environmental problems, such as loss of biodiversity [5], greenhouse gas emissions [6], soil degradation [7], and alteration of hydrological cycles [8], among many others. While these issues are of global relevance, we recognize that they are local in nature since their effects are felt locally, while the actions on the land are performed by local actors whose decisions are driven not only by global [9,10], but also by regional [11] and local [12] forces.Given the great heterogeneity of sociocultural, economic and ecological conditions, it is quite challenging to develop sound theoretical propositions, to identify appropriate empirical approaches for testing them, and to synthesize across the myriad actions on the land, the factors influencing them, and their individual and aggregate consequences. The maturing science of land change [13,14] has emerged to provide such a foundation, and the undertaking is central to the mandate of the Global Land Programme (GLP), which continues a long tradition of producing generalized knowledge on land change [15]. The papers presented in this Special Issue arose from a symposium organized at the GLP's 3rd Open Science Meeting in Beijing, reporting mainly on projects supported by the Belmont Forum call on Food Security and Land Use Change, and organized by the GLP North American Nodal Office. Normally, as editors, we would seek to provide some level of synthesis from the findings presented herein, as a contribution to the effort to generate generalized knowledge. However, we find ourselves hampered in this endeavor by two issues that are emblematic of the land change field as a whole.First, while the Special Issue consists of a very small sample of the rapidly growing literature on land change, the contributions nevertheless address a wide array of land systems and focal processes, including agricultural intensification through the lens of telecoupling [16], the socioeconomic impacts of increasing production of a single crop commodity [17], spatial co-occurrence of food insecurity and biodiversity [18], increasing food security through the use of conservation agriculture [19], assessing whether food production can meet future needs [20,21], and developing strategies for modeling land use, food production and trade [22]. Furthermore, the studies address these issues across several continents (i.e., South America, Europe and Asia) and concern varying agricultural...