Manifestations cardiaques et pulmonaires artérielles au cours d’une maladie de Behçet

Bono, W.; Filali-Ansary, N.; Mohattane, A.; Tazi-Mezalek, Z.; Adnaoui, M.; Aouni, M.; Maaouni, A.; Berbich, A

doi:10.1016/s0248-8663(00)00244-7

Cited by 14 publications

(4 citation statements)

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“…The coexistence of thrombosis and aneurysms is a peculiar feature of Behçet. Retrospective evaluations and expert experience [ 6 , 11 , 13 , 42 - 44 ] Treatment - the management of vascular thrombosis is based on immunosuppressants rather than anticoagulants. Azathioprine and cyclosporine in association with low dose corticosteroids are usually the first choice in the treatment of deep vein thrombosis and superficial vein thrombosis, while cyclophosphamide is the suggested treatment for arterial involvement.…”

Section: Introductionmentioning

confidence: 99%

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Thrombosis in vasculitis: from pathogenesis to treatment

et al. 2015

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In recent years, the relationship between inflammation and thrombosis has been deeply investigated and it is now clear that immune and coagulation systems are functionally interconnected.Inflammation-induced thrombosis is by now considered a feature not only of autoimmune rheumatic diseases, but also of systemic vasculitides such as Behçet’s syndrome, ANCA-associated vasculitis or giant cells arteritis, especially during active disease.These findings have important consequences in terms of management and treatment. Indeed, Behçet’syndrome requires immunosuppressive agents for vascular involvement rather than anticoagulation or antiplatelet therapy, and it is conceivable that also in ANCA-associated vasculitis or large vessel-vasculitis an aggressive anti-inflammatory treatment during active disease could reduce the risk of thrombotic events in early stages.In this review we discuss thrombosis in vasculitides, especially in Behçet’s syndrome, ANCA-associated vasculitis and large-vessel vasculitis, and provide pathogenetic and clinical clues for the different specialists involved in the care of these patients.

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Section: Introductionmentioning

confidence: 99%

“…Thus, the coexistence of thrombosis and aneurysms is a peculiar feature of BS. Overall, cardiac manifestations are rare in BS patients, with a reported incidence between 1% and 6%, and are mainly represented by intracardiac thrombosis and coronary artery disease [ 44 ].…”

Section: Introductionmentioning

confidence: 99%

Thrombosis in vasculitis: from pathogenesis to treatment

et al. 2015

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“…Classiquement, le thrombus intracardiaque secondaire à la maladie de Behçet est adhérent à la paroi, expliquant ainsi sa nature peu emboligène. Néanmoins, des emboles secondaires à des thrombi intracardiaques dans le cadre de maladie de Behçet ont été rapportés [ 7 , 8 ]. L'association d´un thrombus intracardiaque avec une thrombose veineuse est observée dans 56% des cas [ 9 ].…”

Section: Discussionunclassified

Une manifestation exceptionnelle de la maladie de Behçet: la thrombose du ventricule gauche: a propos d´un cas

Berrajaa¹,

Meghraoui²,

Ofkire³

et al. 2023

Pan Afr Med J

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Dans la maladie de Behçet, la survenue de thrombose intracardiaque est rare, exceptionnellement révélatrice. Nous rapportons le cas d´un patient âgé de 48 ans, suivi pour un érythème noueux, admis pour prise en charge d´un accident vasculaire cérébral (AVC). L´interrogatoire objective une aphtose buccale récurrente. L´examen cardiovasculaire était sans particularité, imagerie par résonance magnétique (l´IRM) objectivait un AVC pariétal postérieur gauche. Une échocardiographie trans-thoracique a été réalisée objectivant un anévrysme apical totalement thrombosé mesurant 42mm/36mm; un scanner du corps entier à la recherche d´autres localisations était sans particularité en dehors de l´atteinte cardiaque. Le diagnostic de la maladie de Behçet a été retenu devant l´association d´aphtose buccale récurrente, de l´érythème noueux et de l´anévrysme thrombosé du ventricule gauche. L´évolution était favorable sous traitement médical associant la corticothérapie, l´anticoagulation et l´immunosuppression. La découverte de thrombus intracardiaque ou d´anévrysme ventriculaire chez un jeune homme, résident en région d´endémie devrait faire suspecter la maladie de Behçet, dont le pronostic est principalement en relation avec la gravité de l´atteinte cardiovasculaire.

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“…[34] Although the vascular lesions are frequently observed in this disease, the cardiac involvement is rare and is associated with the poor prognosis. [5]…”

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confidence: 99%

Intracardiac thrombus in Behçet's disease

Eren

Öcal

Kalçık

et al. 2016

J Cardiovasc Echography

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Behçet's disease (BD) is a chronic multisystem disease that presents with recurrent oral and genital ulceration and recurrent uveitis. The patients are often diagnosed in the range of 20-30 years of age and BD are more common in men.[1] BD has a worldwide distribution, but it is mainly observed in Mediterranean areas and Japan.[2] Involvement of skin, joints, nervous, respiratory, gastrointestinal, and cardiovascular systems is also recognised.[34] Although the vascular lesions are frequently observed in this disease, the cardiac involvement is rare and is associated with the poor prognosis.[5]

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Manifestations cardiaques et pulmonaires artérielles au cours d’une maladie de Behçet

Cited by 14 publications

References 1 publication

Thrombosis in vasculitis: from pathogenesis to treatment

Thrombosis in vasculitis: from pathogenesis to treatment

Une manifestation exceptionnelle de la maladie de Behçet: la thrombose du ventricule gauche: a propos d´un cas

Intracardiac thrombus in Behçet's disease

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