Manifestations cliniques chez les sujets exposés à un accident toxique environnemental (Abidjan, Côte d’Ivoire 2006)

Kouassi, B.; Horo, K.; Godé, C.; Ahui, B.J.M.; Achi, V.; Anon, J.C.; Koffi, N.; Ngom, Ablaye; Aka-Danguy, É.; Koffi, Missa; Itchy, M.; Koné, K.; Manewa, S.F.

doi:10.1016/j.rmr.2014.01.015

Cited by 8 publications

(12 citation statements)

References 12 publications

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“…Studies on acute effects in populations living near illegal dump sites in Abidjan [23, 24] provided sufficient evidence of association between exposure to oil industry waste and general and neurological acute symptoms, and specifically otolaryngological, respiratory, digestive and dermatological symptoms (Additional file 3: Table S3).…”

Section: Resultsmentioning

confidence: 99%

“…This evaluation was based on two cross-sectional studies performed in the population resident in Abidjan near the sites where approximately 500 tons of hazardous waste was illegaly dumped and subsequently emitted hydrogen sulphid into the air [23, 24]. The two studies were evaluated respectively as being of high and moderate/high quality (rated 5–4).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Hazardous waste and health impact: a systematic review of the scientific literature

et al. 2017

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Waste is part of the agenda of the European Environment and Health Process and included among the topics of the Sixth Ministerial Conference on Environment and Health. Disposal and management of hazardous waste are worldwide challenges. We performed a systematic review to evaluate the evidence of the health impact of hazardous waste exposure, applying transparent and a priori defined methods. The following five steps, based on pre-defined systematic criteria, were applied. 1. Specify the research question, in terms of “Population-Exposure-Comparators-Outcomes” (PECO). Population: people living near hazardous waste sites; Exposure: exposure to hazardous waste; Comparators: all comparators; Outcomes: all diseases/health disorders. 2. Carry out the literature search, in Medline and EMBASE. 3. Select studies for inclusion: original epidemiological studies, published between 1999 and 2015, on populations residentially exposed to hazardous waste. 4. Assess the quality of selected studies, taking into account study design, exposure and outcome assessment, confounding control. 5. Rate the confidence in the body of evidence for each outcome taking into account the reliability of each study, the strength of the association and concordance of results.Fifty-seven papers of epidemiological investigations on the health status of populations living near hazardous waste sites were selected for the evidence evaluation. The association between 95 health outcomes (diseases and disorders) and residential exposure to hazardous waste sites was evaluated. Health effects of residential hazardous waste exposure, previously partially unrecognized, were highlighted. Sufficient evidence was found of association between exposure to oil industry waste that releases high concentrations of hydrogen sulphide and acute symptoms. The evidence of causal relationship with hazardous waste was defined as limited for: liver, bladder, breast and testis cancers, non-Hodgkin lymphoma, asthma, congenital anomalies overall and anomalies of the neural tube, urogenital, connective and musculoskeletal systems, low birth weight and pre-term birth; evidence was defined as inadequate for the other health outcomes. The results, although not conclusive, provide indications that more effective public health policies on hazardous waste management are urgently needed. International, national and local authorities should oppose and eliminate poor, outdated and illegal practices of waste disposal, including illegal transboundary trade, and increase support regulation and its enforcement.Electronic supplementary materialThe online version of this article (10.1186/s12940-017-0311-8) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Hazardous waste and health impact: a systematic review of the scientific literature

et al. 2017

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“…The evidence of the association between general and neurological acute symptoms, in particular those regarding otolaryngological, respiratory and digestive systems and the skin, and exposure to oil industry waste releasing high concentrations of hydrogen sulphide was evaluated as sufficient. This evaluation was based on two cross-sectional studies performed in the population resident in Abidjan near the sites where approximately 500 tons of hazardous waste was illegaly dumped and subsequently emitted hydrogen sulphid into the air [23,24]. The two studies were evaluated respectively as being of high and moderate/high quality (rated 5-4).…”

Section: Discussionmentioning

confidence: 99%

Hazardous waste and health impact: a systematic review of the scientific literature

Fazzo¹,

Minichilli²,

Santoro³

et al. 2016

ISEE Conference Abstracts

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Waste is part of the agenda of the European Environment and Health Process and included among the topics of the Sixth Ministerial Conference on Environment and Health. Disposal and management of hazardous waste are worldwide challenges. We performed a systematic review to evaluate the evidence of the health impact of hazardous waste exposure, applying transparent and a priori defined methods. The following five steps, based on pre-defined systematic criteria, were applied. 1. Specify the research question, in terms of "Population-Exposure-Comparators-Outcomes" (PECO). Population: people living near hazardous waste sites; Exposure: exposure to hazardous waste; Comparators: all comparators; Outcomes: all diseases/health disorders. 2. Carry out the literature search, in Medline and EMBASE. 3. Select studies for inclusion: original epidemiological studies, published between 1999 and 2015, on populations residentially exposed to hazardous waste. 4. Assess the quality of selected studies, taking into account study design, exposure and outcome assessment, confounding control. 5. Rate the confidence in the body of evidence for each outcome taking into account the reliability of each study, the strength of the association and concordance of results. Fifty-seven papers of epidemiological investigations on the health status of populations living near hazardous waste sites were selected for the evidence evaluation. The association between 95 health outcomes (diseases and disorders) and residential exposure to hazardous waste sites was evaluated. Health effects of residential hazardous waste exposure, previously partially unrecognized, were highlighted. Sufficient evidence was found of association between exposure to oil industry waste that releases high concentrations of hydrogen sulphide and acute symptoms. The evidence of causal relationship with hazardous waste was defined as limited for: liver, bladder, breast and testis cancers, non-Hodgkin lymphoma, asthma, congenital anomalies overall and anomalies of the neural tube, urogenital, connective and musculoskeletal systems, low birth weight and pre-term birth; evidence was defined as inadequate for the other health outcomes. The results, although not conclusive, provide indications that more effective public health policies on hazardous waste management are urgently needed. International, national and local authorities should oppose and eliminate poor, outdated and illegal practices of waste disposal, including illegal transboundary trade, and increase support regulation and its enforcement.

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“…Одним із таких критичних епі зодів можна вважати сепсис новонароджених, який, відповідно до гіпотези [5,6], може відрізнятися за своїм перебігом у тих випадках захворювання, коли батьки проживають у більш сприятливій екологічній обстановці. Слід визнати, що ця гіпотеза підтверджена в численних дослідженнях серед дорослих [7,8], однак подібні дослідження майже не проводи лися серед дітей, хоча є актуальними і перспек тивними як у плані профілактики порушень розвитку плода, так і стосовно раціонального ведення новонароджених, хворих на сепсис.…”

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Mathematical model of sepsis of newborn, whose parents lived in places of different environmental situation

Besrukov¹,

Vlasova²,

Trekush³

2020

MPU

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Мета-створити математичну модель у новонароджених, хворих на неонатальний сепсис, батьки яких проживали в місцях із різною екологічною обстановкою, для подальшого удосконалення менеджменту сепсису новонароджених, батьки яких проживали в місцях із несприятливою екологічною обстановкою. Матеріали та методи. Обстежено 260 новонароджених, хворих на неонатальний сепсис, народжених від батьків, які проживали в різних екологічних умовах. Групоформувальною ознакою комплексної оцінки тривалого навантаження на організм батьків новонароджених антропогенного забруднення повітря, води і ґрунту в районах областей був запропонований коефіцієнт екологічного ризику (КЕР) з урахуванням екологічної обстановки в обласних центрах. Результати. Проведений аналіз взаємозв'язку показників комплексного обстеження хворих на сепсис показав, що між екологічною обстановкою місць проживання батьків новонароджених, факторами ризику розвитку неонатального сепсису та його клінічно лабораторними проявами існує вірогідний зв'язок. Установлено, що в створеній математичній моделі тяжкості сепсису новонароджених, батьки яких проживали в місцях підвищеного екологіч ного ризику, основними компонентами головних факторів були КЕР, малий гестаційний вік, фактори ризику розвитку раннього і пізнього сепсису, показники метаболічного і дихального ацидозу, підвищений вміст у крові інтерлейкіну 8 і поліорганна дисфункція, а також наявність апоптозу. Висновки. Математична модель неонатального сепсису, створена за допомогою багатофакторного кореляційного аналізу, свідчить про наявність двох фенотипів сепсису новонароджених, в основі яких лежить екологічна характеристика місць проживання батьків хворих дітей. На базі вищезазначено го в подальшому буде створено алгоритм менеджменту сепсису новонароджених. Дослідження виконано відповідно до принципів Гельсінської Декларації. Протокол дослідження ухвалено Локальним етичним комітетом зазначеної в роботі установи. На проведення досліджень отримано інформовану згоду батьків дітей. Автори заявляють про відсутність конфлікту інтересів. Ключові слова: неонатальний сепсис, коефіцієнт екологічного ризику, математична модель.

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Manifestations cliniques chez les sujets exposés à un accident toxique environnemental (Abidjan, Côte d’Ivoire 2006)

Cited by 8 publications

References 12 publications

Hazardous waste and health impact: a systematic review of the scientific literature

Hazardous waste and health impact: a systematic review of the scientific literature

Hazardous waste and health impact: a systematic review of the scientific literature

Mathematical model of sepsis of newborn, whose parents lived in places of different environmental situation

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