Manipulating Files

Wang, Wallace

doi:10.1007/978-1-4842-1913-3_6

Cited by 1 publication

(2 citation statements)

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“…To further integrate with other software, we aim to add support for non CSV/text-based output formats like pepXML 53 or pepXMLTab. 54…”

Section: Discussionmentioning

confidence: 99%

“…Future functionalities currently already under development include integration of PPI databases such as String and CORUM to groups based on known complexes, further integration with the HADDOCK software for structural modeling, implementation of true distance measures like, for example, Xwalk implements, integration with standardization efforts like mzIdentMl, and many others. To further integrate with other software, we aim to add support for non CSV/text-based output formats like pepXML or pepXMLTab …”

Section: Discussionmentioning

confidence: 99%

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Cross-ID: Analysis and Visualization of Complex XL–MS-Driven Protein Interaction Networks

et al. 2018

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Protein interactions enable much more complex behavior than the sum of the individual protein parts would suggest and represents a level of biological complexity requiring full understanding when unravelling cellular processes. Cross-linking mass spectrometry has emerged as an attractive approach to study these interactions, and recent advances in mass spectrometry and data analysis software have enabled the identification of thousands of cross-links from a single experiment. The resulting data complexity is, however, difficult to understand and requires interactive software tools. Even though solutions are available, these represent an agglomerate of possibilities, and each features its own input format, often forcing manual conversion. Here we present Cross-ID, a visualization platform that links directly into the output of XlinkX for Proteome Discoverer but also plays well with other platforms by supporting a user-controllable text-file importer. The platform includes features like grouping, spectral viewer, gene ontology (GO) enrichment, post-translational modification (PTM) visualization, domains and secondary structure mapping, data set comparison, previsualization overlap check, and more. Validation of detected cross-links is available for proteins and complexes with known structure or for protein complexes through the DisVis online platform ( ). Graphs are exportable in PDF format, and data sets can be exported in tab-separated text files for evaluation through other software.

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“…To further integrate with other software, we aim to add support for non CSV/text-based output formats like pepXML 53 or pepXMLTab. 54…”

Section: Discussionmentioning

confidence: 99%