Manipulation of nucleation and polymorphism by laser irradiation

Sugiyama, Teruki; Wang, Shun Fa

doi:10.1016/j.jphotochemrev.2022.100530

Cited by 16 publications

(16 citation statements)

References 117 publications

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“…22 The results of these experiments have opened the door to new discussions concerning the control of nucleation mechanism as well as properties of resulting crystal in high-intensity laser-induced nucleation (HILIN). 23,76 3.2. Proposed Mechanism.…”

Section: High-intensity Laser-induced Nucleation (Hilin)mentioning

confidence: 99%

A Review of Laser-Induced Crystallization from Solution

Vikram

Nagaraj

Marques

et al. 2023

Crystal Growth & Design

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Crystallization abounds in nature and industrial practice. A plethora of indispensable products ranging from agrochemicals and pharmaceuticals to battery materials are produced in crystalline form in industrial practice. Yet, our control over the crystallization process across scales, from molecular to macroscopic, is far from complete. This bottleneck not only hinders our ability to engineer the properties of crystalline products essential for maintaining our quality of life but also hampers progress toward a sustainable circular economy in resource recovery. In recent years, approaches leveraging light fields have emerged as promising alternatives to manipulate crystallization. In this review article, we classify laser-induced crystallization approaches where light-material interactions are utilized to influence crystallization phenomena according to proposed underlying mechanisms and experimental setups. We discuss nonphotochemical laser-induced nucleation, high-intensity laser-induced nucleation, laser trapping-induced crystallization, and indirect methods in detail. Throughout the review, we highlight connections among these separately evolving subfields to encourage the interdisciplinary exchange of ideas.

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Section: High-intensity Laser-induced Nucleation (Hilin)mentioning

confidence: 99%

A Review of Laser-Induced Crystallization from Solution

Vikram

Nagaraj

Marques

et al. 2023

Crystal Growth & Design

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“…The NPLIN technique is a complex phenomenon, and there is still debate about the possible mechanisms involved. 16,17 However, to the best of our knowledge, NPLIN has never led to a new crystalline structure (polymorphs or hydrates). 80% of active pharmaceutical ingredients (API) are commercialized in solid forms (crystalline or amorphous phase).…”

Section: ■ Introductionmentioning

confidence: 98%

“…Alexander and Camp 16 limit the use of the NPLIN terms to the nucleation of supersaturated solutions or supercooled melts using unfocused millijoule nanosecond laser pulses. Sugiyama and Wang 17 in a very recent paper have compiled all the experiments included in the Clair et al definition under the term laser-induced nucleation. In this paper, we will use the abbreviation NPLIN, for all the laser-induced nucleation experiments, while their putative mechanism should be different depending, for example, on the laser type.…”

Section: Introductionmentioning

confidence: 99%

“…For a better understanding of this method and thus to contribute to the broadening of its use, Clair et al extended the definition of NPLIN to any nucleation experiment of a supersaturated solution crystallizing after being illuminated by a laser beam. Alexander and Camp limit the use of the NPLIN terms to the nucleation of supersaturated solutions or supercooled melts using unfocused millijoule nanosecond laser pulses. Sugiyama and Wang in a very recent paper have compiled all the experiments included in the Clair et al definition under the term laser-induced nucleation.…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, the crystalline state (powder, multicrystal, or single crystal) can be controlled (see, for example, ref ). The NPLIN technique is a complex phenomenon, and there is still debate about the possible mechanisms involved. , However, to the best of our knowledge, NPLIN has never led to a new crystalline structure (polymorphs or hydrates).…”

Section: Introductionmentioning

confidence: 99%

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New Cocrystallization Method: Non-photochemical Laser-Induced Nucleation of a Cocrystal of Caffeine–Gallic Acid in Water

Mellah

Nicolaı̈

Fournier

et al. 2022

Crystal Growth & Design

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This paper reports for the first time the crystallization of cocrystals (caffeine -gallic acid) in water using the Non-Photochemical Laser-Induced Nucleation (NPLIN) technique. The nucleation temporal control of NPLIN and the induction time reduction (70 times shorter than spontaneous nucleation) allow the obtention of cocrystals on-demand, with excellent repeatability. Prior to NPLIN experiments, solubility measurements, metastable zone limit determination, and spontaneous nucleation (SN) are carried out. Supersaturated solutions at three different molarities of caffeine (0.0158, 0.0167 and 0.0179 M) are prepared and dissolved at 338 K. Supersaturated solutions are exposed to a 532 nm wavelength nanosecond pulsed laser at 296 K. Some hours later crystals can be filtered. The impact of supersaturation on probability of nucleation has been studied and the result shows a higher supersaturation implies a higher probability of nucleation. Crystalline form characterization has employed a combination of Raman scattering, high-performance liquid chromatography, thermogravimetry, differential scanning calorimetry, and powder X-ray diffraction; the sizes of the cocrystals being too small for a single-crystal X-ray diffraction experiment. Two different cocrystal forms are obtained: a new polymorph of hemihydrate CAFGAL.0.5H2O from spontaneous nucleation by precipitation, and a new hydrate form CAFGAL.1.5H2O from NPLIN and from spontaneous nucleation of a supersaturated solution without evaporation. These results open a promising way to crystallize cocrystals in the context of the pharmaceutical industry.

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Aggregation‐Induced Emission (AIE) of Au(I)‐GSH Complexes is Activated by Optical Manipulation and Exhibits Surprising 780 nm Emission

Xu,

Yu,

Liu

et al. 2024

Advanced Optical Materials

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An optical manipulation method to activate the aggregation‐induced emission (AIE) of Au(I)‐glutathione (Au(I)‐GSH) complexes is presented. First, the well‐known AIE‐type Au(I)‐GSH complexes with a solid emission wavelength of 570 nm are synthesized. At the beginning of the focusing a 1064 nm continuous‐wave (CW) laser at the interface of Au(I)‐GSH complexes solution, its luminescence is hardly detectable. However, with the extension of the laser irradiation time, aggregate appears and rapidly grows, and strong luminescence is shown, indicating the activation of AIE of Au(I)‐GSH complexes through optical manipulation. Surprisingly, the emission peak is at 780 nm and no blue‐shift is observed with the emission intensity increases. The activated AIE emission wavelength by optical manipulation is longer than reported previously, which means that optical manipulation activates AIE in a unique manner. The switching on/off of the activation of AIE is arbitrarily controlled by changing the laser power. In this paper, the luminescence phenomenon and mechanism of AIE are discussed from the perspective of the movement limitation of Au(I)‐GSH complexes under optical manipulation. It is of significant importance for further insights into the luminescence of Au(I)‐GSH complexes and their future development.

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Manipulation of nucleation and polymorphism by laser irradiation

Cited by 16 publications

References 117 publications

A Review of Laser-Induced Crystallization from Solution

A Review of Laser-Induced Crystallization from Solution

New Cocrystallization Method: Non-photochemical Laser-Induced Nucleation of a Cocrystal of Caffeine–Gallic Acid in Water

Aggregation‐Induced Emission (AIE) of Au(I)‐GSH Complexes is Activated by Optical Manipulation and Exhibits Surprising 780 nm Emission

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