Manipulations and age-appropriateness of oral medications in pediatric oncology patients in Sweden: Need for personalized dosage forms

Johannesson, J. K.; Hansson, Paula; Bergström, Christel A. S.; Paulsson, Mattias

doi:10.1016/j.biopha.2021.112576

Cited by 13 publications

(4 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, dose adjustment is required considering the age of the pediatric patient. To overcome these limitations, orally disintegrating formulations are widely manufactured [4,5].…”

Section: Introductionmentioning

confidence: 99%

A new approach to oral dosage forms: carrageenan-based vegan gummies

Ezgi GÜLTEKİN,

İLHAN,

NALBANTOĞLU

2024

jrp

View full text Add to dashboard Cite

show abstract

“…In addition, dose adjustment is required considering the age of the pediatric patient. To overcome these limitations, orally disintegrating formulations are widely manufactured [4,5].…”

Section: Introductionmentioning

confidence: 99%

A new approach to oral dosage forms: carrageenan-based vegan gummies

Ezgi GÜLTEKİN,

İLHAN,

NALBANTOĞLU

2024

jrp

View full text Add to dashboard Cite

show abstract

“…Medication errors and non-adherence to medicine regimens is a significant cost burden to health services [6]. Whilst a significant volume of research has been conducted in the paediatric population [17][18][19], the aim of this systematic review is to identify and critically appraise the available evidence regarding oral medicine administration to adult inpatients in a variety of healthcare settings, such as (1) in hospitals, (2) nursing homes and (3) long-term stay units (LTSUs).…”

Section: Introductionmentioning

confidence: 99%

Adult Patients with Difficulty Swallowing Oral Dosage Forms: A Systematic Review of the Quantitative Literature

Harnett,

Byrne,

O’Connor

et al. 2023

Pharmacy

View full text Add to dashboard Cite

The aim of this systematic review was to identify and critically appraise the available evidence regarding solid oral dosage forms (SODFs), e.g., tablets, and challenges regarding the oral administration of medicine to inpatients in a variety of healthcare settings such as (1) hospitals, (2) nursing homes and (3) long-term stay units (LTSUs). A literature search was undertaken in September 2021 and repeated in June 2023 in the following databases: PubMed, EMBASE, CINAHL, Scopus, Web of Science, The Cochrane Library, PsycINFO and ProQuest. A Microsoft Excel® spreadsheet was devised to collate the following data from each eligible study: study author and year, country, number of participants, title, duration (follow-up period), study design, inclusion and exclusion criteria, method and data collection, relevant outcomes, and key findings. A total of 3023 records were identified, with 12 articles being included in the final systematic review. Seven of the twelve studies reported on the prevalence of difficulties swallowing SODFs, which varied from 10–34.2%. Nine of the twelve studies reported the methods used to manipulate SODFs, with the most reported method being tablet crushing. Given the prevalence of swallowing difficulties and the subsequent crushing of medicines in response to this, it is evident that concerns should be raised regarding the potential for a medication administration error to occur.

show abstract

“…Oral dosage forms constitute one of the most common pharmaceutical drug products since the oral route usually is the preferred route of drug administration. Even though oral dosage forms have been intensively used over the last centuries in all fields of medicine, there is a lack of age-appropriate formulations [1]. Pediatric patients are of particular concern and require appropriate dosage forms containing an accurate dose, which are often not commercially available.…”

Section: Introductionmentioning

confidence: 99%