“…Spinal manipulation, particularly when performed on the upper cervical spine, is associated with minor to moderate adverse effects in clinical populations (Carlesso et al, 2010b;Carnes et al, 2010a;Ernst, 2007;Rubinstein, 2008;Senstad et al, 1996). This has been has been a professional concern for some decades (Carlesso and Rivett, 2011;Carlesso, Gross, 2010b;Carlesso et al, 2013;Kerry et al, 2008;Taylor and Kerry, 2005). While the risk of major adverse effects with manipulation is low, 50e60% of manual therapy patients may experience minor to moderate adverse effects after treatment (Cagnie et al, 2004;Carlesso et al, 2010b;Carnes, Mars, 2010a;Ernst, 2007;Hurwitz et al, 2005;Paanalahti et al, 2014).…”