Manno-oligosaccharides as Prebiotic-Valued Products from Agro-waste

Singh, Shweta; Ghosh, Arabinda; Goyal, Arun

doi:10.1007/978-981-10-7434-9_12

Cited by 17 publications

(14 citation statements)

References 65 publications

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“…Many authors have demonstrated the prebiotic effect of different polysaccharides from agricultural waste; in vitro experiments performed with XOS extracted from barley straw demonstrated their suitability for use as a prebiotic ingredient [ 52 ]. Another type of hemicellulosic polysaccharide that demonstrates prebiotic character is MOS as they resist digestion in the upper gastrointestinal tract [ 53 ]. Pectic polysaccharides have also shown prebiotic activity.…”

Section: Polysaccharides From Agricultural Wastementioning

confidence: 99%

Strategies to Increase the Biological and Biotechnological Value of Polysaccharides from Agricultural Waste for Application in Healthy Nutrition

Rivas

Casquete

Martı́n

et al. 2021

IJERPH

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Nowadays, there is a growing interest in the extraction and identification of new high added-value compounds from the agro-food industry that will valorize the great amount of by-products generated. Many of these bioactive compounds have shown beneficial effects for humans in terms of disease prevention, but they are also of great interest in the food industry due to their effect of extending the shelf life of foods by their well-known antioxidant and antimicrobial activity. For this reason, an additional research objective is to establish the best conditions for obtaining these compounds from complex by-product structures without altering their activity or even increasing it. This review highlights recent work on the identification and characterization of bioactive compounds from vegetable by-products, their functional activity, new methodologies for the extraction of bioactive compounds from vegetables, possibly increasing their biological activity, and the future of the global functional food and nutraceuticals market.

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Section: Polysaccharides From Agricultural Wastementioning

confidence: 99%

Strategies to Increase the Biological and Biotechnological Value of Polysaccharides from Agricultural Waste for Application in Healthy Nutrition

Rivas

Casquete

Martı́n

et al. 2021

IJERPH

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“…Mannooligosaccharides are derived from mannan in biomass, and thus are typically made up of mannose subunits connected by β-1,4 bonds [15]. Isomaltooligosaccharides (IMOS) contain glucose subunits, but vary in their bonding structure (affected by manufacturing method).…”

Section: Chemical Structures Of Prebioticsmentioning

confidence: 99%

Functional Attributes and Health Benefits of Novel Prebiotic Oligosaccharides Derived from Xylan, Arabinan, and Mannan

Saville¹,

Saville²

2020

Prebiotics and Probiotics - Potential Benefits in Nutrition and Health

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Prebiotic oligosaccharides are produced from many different sources, with substantial differences in chemical structure, bonds between subunits, and degree of polymerization. These structural differences can materially affect microbial utilization and the dose required for efficacy. Most prebiotic oligosaccharides are based on subunits comprised of 6-carbon sugars such as glucose/fructose and alpha bonds. Newer/novel oligosaccharides are derived from 5 carbon sugars and/or connected via beta bonds. Clinical trials with xylooligosaccharides, arabinoxylanoligosaccharides, and mannooligosaccharides have shown improvements in lipids, cholesterol, management of blood glucose, weight management, and laxation, at doses typically ranging from 1 to 4 g per day. Mannooligosaccharides are also showing promise for animal health, with the potential to reduce antibiotic use. These novel prebiotics are showing promise due to greater selectivity and their ability to deliver health benefits at a lower dose compared to conventional prebiotics.

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“…Many investigations have been directed at the use of pectin-rich agro-industrial by-products (citrus peel, orange peel, apple pomace) as a source of POS ( Babbar et al, 2016 ). MO are produced by enzymatic hydrolysis of the commercial substrate using β-mannanase ( Singh et al, 2018 ). Attempts have also been made to produce MO from mannan-rich agricultural by-products ( Jian et al, 2013 ; Jana and Kango, 2020 ).…”

Section: Introduction To Prebiotics and Its Typesmentioning

confidence: 99%

Neuroprotective Potential of Non-Digestible Oligosaccharides: An Overview of Experimental Evidence

et al. 2021

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Non-digestible oligosaccharides (NDOs) from dietary sources have the potential as prebiotics for neuroprotection. Globally, diverse populations suffering from one or the other forms of neurodegenerative disorders are on the rise, and NDOs have the potential as supportive complementary therapeutic options against these oxidative-linked disorders. Elevated levels of free radicals cause oxidative damage to biological molecules like proteins, lipids, and nucleic acids associated with various neurological disorders. Therefore, investigating the therapeutic or prophylactic potential of prebiotic bioactive molecules such as NDOs as supplements for brain and cognitive health has merits. Few prebiotic NDOs have shown promise as persuasive therapeutic solutions to counter oxidative stress by neutralizing free radicals directly or indirectly. Furthermore, they are also known to modulate through brain-derived neurotrophic factors through direct and indirect mechanisms conferring neuroprotective and neuromodulating benefits. Specifically, NDOs such as fructo-oligosaccharides, xylo-oligosaccharides, isomalto-oligosaccharides, manno-oligosaccharides, pectic-oligosaccharides, and similar oligosaccharides positively influence the overall health via various mechanisms. Increasing evidence has suggested that the beneficial role of such prebiotic NDOs is not only directed towards the colon but also distal organs including the brain. Despite the wide applications of these classes of NDOs as health supplements, there is limited understanding of the possible role of these NDOs as neuroprotective therapeutics. This review provides important insights into prebiotic NDOs, their source, and production with special emphasis on existing direct and indirect evidence of their therapeutic potential in neuroprotection.

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Manno-oligosaccharides as Prebiotic-Valued Products from Agro-waste

Cited by 17 publications

References 65 publications

Strategies to Increase the Biological and Biotechnological Value of Polysaccharides from Agricultural Waste for Application in Healthy Nutrition

Strategies to Increase the Biological and Biotechnological Value of Polysaccharides from Agricultural Waste for Application in Healthy Nutrition

Functional Attributes and Health Benefits of Novel Prebiotic Oligosaccharides Derived from Xylan, Arabinan, and Mannan

Neuroprotective Potential of Non-Digestible Oligosaccharides: An Overview of Experimental Evidence

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