Manufacture and use of tumescence solution meeting hospital‐required hygiene conditions – practical implications

Volc, Sebastian; Maier, Johannes; Breuninger, Helmut; Hund, Verena; Häfner, Hans‐Martin; Kofler, Lukas

doi:10.1111/jdv.15754

Cited by 19 publications

(27 citation statements)

References 6 publications

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“…Using TLA-solution with added epinephrine, intraoperative bleeding is reduced, and both intra-operative and post-operative analgesia are ensured. Furthermore, TLA can be administered by the surgeons themselves and no anesthetist has to be present [12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Post‐operative follow‐up of 150 patients with sentinel lymph node biopsy under tumescence local anesthesia

Eckardt

Häfner

Kofler

et al. 2021

J Deutsche Derma Gesell

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Background: Sentinel lymph node biopsy (SLNB) is useful for staging of patients with melanoma. Although SLNB is mostly performed under general anesthesia (GA), tumescence local anesthesia (TLA) can also be used. However, less data are available regarding feasibility of SLNB under TLA. Here we present a post-operative follow-up of 150 patients. Patients and Methods:We prospectively analyzed data from 150 patients with primary cutaneous malignant melanoma. We assessed pain, post-operative complications and patients' satisfaction after SLNB under TLA.Results: 32 % of the patients reported post-operative pain within the first 48 h after SLNB. Seroma was the most frequent complication, as 29 seromas after SLNB were observed. Wound infection was observed in 3.3 % of the patients. 98.7 % of the patients were satisfied with SLNB under TLA.Conclusions: SLNB under TLA is a safe and feasible option and should be considered for patients with melanoma. Especially with multimorbid or elderly patients, the risks of GA can be avoided.

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Section: Introductionmentioning

confidence: 99%

Post‐operative follow‐up of 150 patients with sentinel lymph node biopsy under tumescence local anesthesia

Eckardt

Häfner

Kofler

et al. 2021

J Deutsche Derma Gesell

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“…General anaesthesia and tumescent local anaesthesia in dermatosurgery in infants is a suitable outpatient treatment option for small lesions without any major risks or sideeffects and the benefit of prolonged postoperative analgesia [27]. Because tumescent local anaesthesia (TLA) utilizes a mixture of highly diluted local anesthetics in a carrier solution and is used for skin biopsies, excision of skin tumors, and vein surgery [28], it is completely safe [29].…”

Section: Discussionmentioning

confidence: 99%

Risk of General Anesthesia in Pediatric Skin Procedures with Projection on Tumescent Anesthesia

Alajlan

Alhabeeb²,

Al-Hazmi³

et al. 2020

Dermatology Research and Practice

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Background. Uses of general anaesthesia in outpatient invasive procedures have increased, especially in dermatology. Being uncooperative, children often require general anaesthesia, since surgical skin operations are mostly painful. Aim. The purpose of this study is to evaluate the safety, significant adverse events, and the complication rates related to general anaesthesia, when used among pediatric population undergoing skin procedures. Methods. We conducted a first retrospective cohort study of patient chart review during the period from September 1, 2017 through September 2019. All patients admitted for pediatric skin procedures during this period have participated in our study. We reviewed selected charts to document any unexpected admissions, adverse events, or complications. Surgical outcomes and anaesthesia complications were reviewed by three anesthesiologists. We assessed inter-rater reliability. Results. A total of 211 procedures were reported for 211 patients with 19 diagnoses. No adverse events related to anaesthesia were recognized, apart from minor complications noticed in twelve patients. The kappa value range is between 0.78 and 1.00 (95% C.I., 0.46809 to 1.00). Conclusion. Dermatologist and pediatricians can safely do necessary procedures under general anaesthesia with the supervision of pediatric-trained anesthesiologists while considering other safety and risk precautions and the pediatric age group.

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“…Analgesia was provided by subcutaneous infusion of tumescent solution (Figure a). For this purpose, we used the following formulation : Sterofundin ® ISO solution 500 mL, lidocaine 2 % 10 mL, ropivacaine 1 % 10 mL (the latter two are provided by our pharmacy in the form of a mixed solution with extended shelf life ), epinephrine 1 : 1,000 0.5 mL. The maximum volume that can be safely administered is 12 mL/kg of body weight.…”

Section: Techniquementioning

confidence: 99%

Management of giant congenital nevi in infants by excision under local anesthesia

Volc

Götz

Breuninger

et al. 2020

J Deutsche Derma Gesell

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Manufacture and use of tumescence solution meeting hospital‐required hygiene conditions – practical implications

Cited by 19 publications

References 6 publications

Post‐operative follow‐up of 150 patients with sentinel lymph node biopsy under tumescence local anesthesia

Post‐operative follow‐up of 150 patients with sentinel lymph node biopsy under tumescence local anesthesia

Risk of General Anesthesia in Pediatric Skin Procedures with Projection on Tumescent Anesthesia

Management of giant congenital nevi in infants by excision under local anesthesia

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