2024
DOI: 10.1186/s12864-024-10137-0
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Many purported pseudogenes in bacterial genomes are bona fide genes

Nicholas P. Cooley,
Erik S. Wright

Abstract: Background Microbial genomes are largely comprised of protein coding sequences, yet some genomes contain many pseudogenes caused by frameshifts or internal stop codons. These pseudogenes are believed to result from gene degradation during evolution but could also be technical artifacts of genome sequencing or assembly. Results Using a combination of observational and experimental data, we show that many putative pseudogenes are attributable to erro… Show more

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