2012
DOI: 10.1152/ajpheart.01185.2010
|View full text |Cite
|
Sign up to set email alerts
|

Mapping 3-D functional capillary geometry in rat skeletal muscle in vivo

Abstract: Fraser GM, Milkovich S, Goldman D, Ellis CG. Mapping 3-D functional capillary geometry in rat skeletal muscle in vivo. Am J Physiol Heart Circ Physiol 302: H654 -H664, 2012. First published December 2, 2011; doi:10.1152/ajpheart.01185.2010.-We have developed a novel mapping software package to reconstruct microvascular networks in three dimensions (3-D) from in vivo video images for use in blood flow and O2 transport modeling. An intravital optical imaging system was used to collect video sequences of blood fl… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
69
0

Year Published

2012
2012
2025
2025

Publication Types

Select...
5
3

Relationship

3
5

Authors

Journals

citations
Cited by 32 publications
(69 citation statements)
references
References 24 publications
0
69
0
Order By: Relevance
“…Individual vessels within each network geometry were analyzed to measure hematocrit, cell velocity and SO 2 using custom software package similar to that described previously . Vessel segments were selected from functional images of microvascular flow and space‐time images were created from 60 seconds long video sequences.…”
Section: Methodsmentioning
confidence: 99%
“…Individual vessels within each network geometry were analyzed to measure hematocrit, cell velocity and SO 2 using custom software package similar to that described previously . Vessel segments were selected from functional images of microvascular flow and space‐time images were created from 60 seconds long video sequences.…”
Section: Methodsmentioning
confidence: 99%
“…Vascular morphology for complete networks was determined using custom MATLAB (Mathworks, Natick, MA, USA) software that has been previously described [3]. Briefly, multiple intravital video sequences were recorded in overlapping fields at multiple focal depths to capture the complete geometry and connectivity of the network within a region of interest.…”
Section: Methodsmentioning
confidence: 99%
“…In our previous paper, we described an experimental protocol and software package for reconstructing 3D capillary networks from video recordings of microvascular blood flow in vivo [3]. We also described how measurements of RBC velocity, hematocrit, RBC SR, and RBC O 2 saturation in these capillaries were acquired from the same videos used to reconstruct the network.…”
Section: Introductionmentioning
confidence: 99%
“…The images were taken from an in vivo preparation of rat extensor digitorum longus (EDL) muscle. For more information on the in vivo preparation, see the study by Fraser and colleagues …”
Section: Methodsmentioning
confidence: 99%