Evapotranspiration (ET) is a critical component of the water cycle, and an accurate prediction of ET is essential for water resource management, irrigation scheduling, and agricultural productivity. Traditionally, ET has been estimated using satellite-based remote sensing, which provides synoptic coverage but can be limited in spatial resolution and accuracy. Unmanned aerial vehicles (UAVs) offer improved ET prediction by providing high-resolution imagery of the Earth’s surface but are limited to a small area. Therefore, UAV and satellite images provide complementary data, but the integration of these two data for ET prediction has received limited attention. This paper presents a method that integrates UAV and satellite imagery for improved ET prediction and applies it to five crops (corn, rye grass, wheat, and alfalfa) from agricultural fields in the Walla Walla of eastern Washington State. We collected UAV and satellite data for five crops and used the combination of remote sensing models and statistical techniques to estimate ET. We show that UAV-based ET can be integrated with the Landsat-based ET with the application of integration factors. Our result shows that the Root Mean Square Error (RMSE) of daily ET for corn (Zea mays), rye grass (Lolium perenne), wheat (Triticum aestivum), peas (Pisum sativum), and alfalfa (Medicago sativa) can be improved by the application of the integration factor to the Landsat based ET in the range of (35.75–65.52%). We also explore the variability and effect of partial cloud on UAV-based ET estimation. Our findings have implications for the use of UAVs in water resource management and highlight the importance of considering multiple sources of data in ET prediction.