On-chip silicon microcavity sensors are advantageous for the detection of virus and biomolecules due to their compactness and the enhanced light-matter interaction with the analyte. While their theoretical sensitivity is at the single-molecule level, the fabrication of high Q silicon cavities and their integration with optical couplers remain as major hurdles in applications such as single virus detection. Here, we propose and demonstrate the label-free single virus detection using silicon photonic crystal random cavities. The sensor chips consist of free-standing silicon photonic crystal waveguides and do not require pre-fabricated defect cavities or optical couplers. Residual fabrication disorder results in the Anderson-localized cavity modes which are excited by a free space beam. The Q~10 5 is sufficient for observing the discrete step-changes in resonance wavelength for binding of single adenoviruses (~50 nm radius). The CMOS-compatible silicon sensor chips enable biosensors that operate at the level of single nanoparticles and molecules.