Mapping the English and Chinese Versions of the Functional Assessment of Cancer Therapy–General to the EQ-5D Utility Index

Cheung, Yin‐Bun; Thumboo, Julian; Gao, Fei; Ng, Gim-Yew; Pang, Grace Su-Yin; Koo, Wen Hsin; Sethi, Vijay-Kumar; Wee, Joseph; Goh, Cynthia

doi:10.1111/j.1524-4733.2008.00448.x

Cited by 54 publications

(68 citation statements)

References 23 publications

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“…This means that utility scores measured by the EQ-5D do not reflect social and family well-being. A similar result was reported by a study group in Singapore [19]. We found strong correlations between FACT-PWB subscale and utility scores and between FACTTaxane and utility scores.…”

Section: Discussionsupporting

confidence: 89%

Comparison of EQ-5D Scores among Anthracycline-Containing Regimens followed by Taxane and Taxane-Only Regimens for Node-Positive Breast Cancer Patients after Surgery: The N-SAS BC 02 Trial

et al. 2011

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Section: Discussionsupporting

confidence: 89%

Comparison of EQ-5D Scores among Anthracycline-Containing Regimens followed by Taxane and Taxane-Only Regimens for Node-Positive Breast Cancer Patients after Surgery: The N-SAS BC 02 Trial

et al. 2011

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“…The 6-item EQ-5D self-administered questionnaire, designed to assess health status in adults, comprises 2 distinct components: the first addresses domains of mobility, self-care, usual activity, pain/discomfort, and anxiety/depression and the second measures self-rated (global) health status using a visual analog scale [16]. …”

Section: Methodsmentioning

confidence: 99%

Observational Study to Assess Quality of Life in Patients with Pancreatic Neuroendocrine Tumors Receiving Treatment with Everolimus: The OBLIQUE Study (UK Phase IV Trial)

et al. 2019

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Background/Aims: To assess health-related quality of life (HRQoL), treatment patterns, and clinical outcomes of adult (≥18 years) patients with advanced (unresectable or metastatic) pancreatic neuroendocrine neoplasms (PanNENs) treated with everolimus in routine clinical practice. Methods: In a prospective, non-interventional, multi-center study patients administered at least one 10 mg dose of everolimus were evaluated for change in HRQoL (EORTC QLQ-C30 Global Health Status scale) from baseline after 6 months treatment (primary endpoint). Secondary endpoints included disease-specific HRQoL measures (EORTC QLQ-G.I.NET21), clinical outcomes, everolimus treatment patterns, and safety. Results: Forty-eight patients were recruited (between August 2013 and March 2015); the median treatment duration was 27.8 months. EORTC QLQ-C30 Global Health score was not significantly different from baseline after 6 months of treatment (mean difference –1.9 points, p = 0.660, n = 30). In pairwise analyses, the only significant changes in HRQoL from baseline were for EORTC QLQ-C30 physical functioning score at month 3 (adjusted mean difference –8.8 points, p = 0.002, n = 36) and the EORTC QLQ-G.I.NET21 disease-related worries scores at months 1 and 2 (adjusted mean differences: –11.5 points [p = 0.001, n = 44] and –8.8 points [p = 0.017, n = 43], respectively). Disease progression or death was recorded in 44.4% (n = 20/45) patients during follow-up; median progression-free survival was 25.1 months and the cumulative survival rate at 3 years was 71%. No new safety signals were detected. Conclusions: The OBLIQUE study demonstrates that HRQoL is maintained in patients with PanNENs during treatment with everolimus in a UK real-world setting. This study adds to the limited HRQoL data available in this patient group.

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“…Uzun yıllar boyunca yapılmış olan etkinlik çalışmalarından elde edilmiş olan hastalığa-özgü ölçümlerin, günümüzde ekonomik analizler için yeniden kullanılabileceği düşünülmüştür. Bu noktadan yola çıkarak, kanser, koroner kalp hastalığı, Parkinson hastalığı ve inflamatuvar barsak hastalığı gibi çok farklı hastalık gruplarında, hastalığa-özgü ölçeklerin EQ-5D ile eşleştirilmesi için çeşitli modeller geliştirilmiştir (17)(18)(19)(20)(21). Yakın zaman içerisinde, KİS hastalıklarından diz osteoartriti için de benzer çalışmalar yapılmıştır.…”

Section: Discussionunclassified

Fizik Tedavi Programlarının Ağrı ve Hayat Kalitesi Üzerine Etkisi

...

2012

Tftr

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ÖzetAmaç: Kas iskelet sistemi (KİS) hastalıkları bireylerin yaşam kalitesini olumsuz etkileyen ve sağlık harcamalarına ciddi yük oluşturan önemli bir sağlık sorunudur. Bu çalışmanın amacı çeşitli KİS patolojilerinin tedavisinde kullanılan fizik tedavi programlarının ağrı ve hayat kalitesi üzerine etkisini araştırmaktır. Gereç ve Yöntem: Çalışmaya boyun, omuz, diz ve bel bölgesine yönelik fizik tedavi programı uygulanmış olan toplam 160 hasta dahil edildi. Hastaların yaşı, cinsiyeti, hastalara önerilen fizik tedavi modalitelerinin ve egzersizin türü kaydedildi. Tedavi öncesi ve sonrası hastalardan ağrı ve hayat kalitelerindeki değişimi değerlendirmek amacıyla sırasıyla vizüel analog skalayı (VAS) ve EuroQoL-5D (EQ-5D) ölçeğini yanıtlamaları istendi. Bulgular: Hastaların ortalama yaşı 51,8±13,2 (21-85) yıldı. Yüzeyel ısıtıcılardan hotpack, derin ısıtıcılardan ultrason, analjezik akımlardan ise TENS en sık kullanılan modalitelerdi. Hastalara en sık güçlendirme egzersizleri, çok daha az sıklıkla eklem hareket açıklığı ve germe egzersizleri önerilmişti. Hastaların tedavi öncesi VAS skoru 6,7±2,1 (0-10) ve EQ-5D skoru 0,30±0,34 (-0,43-0,90) iken fizik tedavi sonrasında bu değerler sırasıyla 4,3±2,5 (0-10) ve 0,59±0,28 (-0,69-1,00) olarak belirlendi. Kadınlarda erkeklere oranla ağrı şiddeti tedavi öncesi (p=0,022) ve sonrası (p<0,001) daha yüksek, hayat kalitesi daha kötüydü (p<0,001). Her iki cinste de fizik tedavi uygulamaları ile istatistiksel olarak anlamlı düzeyde ağrıda azalma ve hayat kalitesinde düzelme sağlandığı gözlendi (p<0,001). Sonuç: KİS hastalıklarının tedavisinde sıklıkla uygulanmakta olan fizik tedavi programları hastaların bölgesel ağrılarını azalmakta ve hayat kalitelerini arttırmaktadır. Türk Fiz T›p Re hab Derg 2012;58:99-102. Anah tar Ke li me ler: Fizik tedavi, ağrı, hayat kalitesi, EQ-5D Sum maryObjective: Musculoskeletal system (MSS) diseases comprise a major health problem with negative impact on quality of life of individuals and considerable burden on health care systems. The aim of the study was to investigate the effect of physical therapy programs used in the treatment of various MSS disorders on the patients' pain and quality of life. Materials and Methods: 160 patients, who participated in a physical therapy program for their neck, shoulder, knee or low back pain, were included in the study. The patients' age, sex, and the type of the prescribed physical therapy modality and exercise were recorded. Before and after the treatment, in order to evaluate the change in the severity of pain and quality of life, the patients were respectively asked to complete the visual analog scale (VAS) and EuroQoL-5D (EQ-5D) measure. Results: The mean age of the patients was 51.8±13.2 (21-85) years. The most commonly used modalities were hot packs among superficial heaters, ultrasound among deep heaters and TENS among analgesic currents. Whereas the most frequently prescribed exercises were strengthening exercises, stretching and range of motion exercises were rarely recommended. The average pre-treatment...

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Mapping the English and Chinese Versions of the Functional Assessment of Cancer Therapy–General to the EQ-5D Utility Index

Abstract: At the group level, but not individual level, the equation developed can accurately map the English and Chinese versions of the FACT-G scores to the EQ-5D utility index.

Cited by 54 publications

References 23 publications

Comparison of EQ-5D Scores among Anthracycline-Containing Regimens followed by Taxane and Taxane-Only Regimens for Node-Positive Breast Cancer Patients after Surgery: The N-SAS BC 02 Trial

Comparison of EQ-5D Scores among Anthracycline-Containing Regimens followed by Taxane and Taxane-Only Regimens for Node-Positive Breast Cancer Patients after Surgery: The N-SAS BC 02 Trial

Observational Study to Assess Quality of Life in Patients with Pancreatic Neuroendocrine Tumors Receiving Treatment with Everolimus: The OBLIQUE Study (UK Phase IV Trial)

Fizik Tedavi Programlarının Ağrı ve Hayat Kalitesi Üzerine Etkisi

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