2021
DOI: 10.1101/2021.07.05.451183
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Mapping the glycosyltransferase fold landscape using deep learning

Abstract: Glycosyltransferases (GTs) play fundamental roles in nearly all cellular processes through 10 the biosynthesis of complex carbohydrates and glycosylation of diverse protein and small 11 molecule substrates. The extensive structural and functional diversification of GTs presents a 12 major challenge in mapping the relationships connecting sequence, structure, fold and function 13 using traditional bioinformatics approaches. Here, we present a convolutional neural network 14 with attention (CNN-attention) based … Show more

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