Background Exposure to air pollution is one of the primary global health risk factors, yet individuals lack the knowledge to engage in individual risk mitigation and the skills to mobilize for change necessary to reduce such risks. The news media are an important tool for influencing individual actions and support for public policies to reduce environmental threats; thus, a lack of news coverage of such issues may exacerbate knowledge deficits. This study examines the reporting of health risk and precautionary measures regarding air pollution in national and regional print news using an environmental health literacy perspective.Methods We conducted a content analysis of two national (New York Times and Washington Post) and two local newspapers (Fresno Bee and Bakersfield Californian) newspapers covering the country’s most polluted region, California’s San Joaquin Valley, during a 5-year period (2011-2015). Using a constructed week sampling approach, 276 newspaper articles were coded for information on threat, efficacy information, and information sources.Results News coverage of air pollution mostly failed to mention human health risks. Moreover, fewer than 10 percent of news stories about air pollution provided information on the precautionary measures necessary for individuals to take action to mitigate their risk. Despite being located in one of the most polluted areas in the US, local newspapers did not report significantly more threat and efficacy information. News coverage of air pollution consistently missed opportunities to raise environmental health literacy.Conclusions Although air pollution levels are high and continue to rise at alarming rates, our findings suggest that news media reporting is not conducive to raising environmental health literacy. Public health advocates and health promotion experts must develop more effective strategies for disseminating information about the health risks of air pollution, balancing the need for recognizing the structural causes of poor air quality and the actions individuals and communities can take to reduce air pollution related morbidity and mortality. National and local news media may be useful partners for such dissemination.