Mapping the orbitofrontal cortex using temporal fluctuations in cerebral blood flow

Petersen, Kalen J.; Donahue, Manus J.; Claassen, Daniel O.

doi:10.1002/brb3.2034

Cited by 2 publications

(1 citation statement)

References 49 publications

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“…In drawing the ROI manually, identification and avoidance of artifacts is also very important to avoid affecting the accuracy of R2* values. The magnetic susceptibility artifact in BOLD-MRI is usually displayed as a low-signal intensity in an echo image and a high-signal intensity in an R2* mapping [ 20 ]. Motion artifacts mainly occur in the upper pole of kidney, and most of them are bilaterally symmetric and thus easily distinguished.…”

Section: Discussionmentioning

confidence: 99%

Cortical and medullary oxygenation evaluation of kidneys with renal artery stenosis by BOLD-MRI

Zhao

Li²,

Meng

et al. 2022

PLoS ONE

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Aim Blood oxygen level–dependent magnetic resonance imaging (BOLD-MRI) can measure deoxyhemoglobin content. This study aims to evaluate the capacity of BOLD-MRI, which is possible to evaluate the oxygenation state of kidneys with renal artery stenosis (RAS). Materials and methods We performed BOLD-MRI for 40 patients with RAS and for 30 healthy volunteers. We then performed post-scan processing and analysis of manually drawn regions of interest to determine R2* values (relaxation rates) for the renal cortex and medulla. We compared R2* values in patients with RAS with those in the control group, and also compared these values for subgroups with varying degrees of stenosis. Results Medulla R2* values were higher than cortex R2* values in the control group. There was no significant difference in R2* values for different segments (upper, middle, lower) of the kidneys. Both cortex and medulla R2* values in patients with RAS were significantly higher than corresponding R2* values in the control group (P < 0.05), and BOLD-MRI was more sensitive to changes in the R2* values in the medulla than in the cortex. Among different subgroups in the RAS group, the medulla R2* values were significantly higher in kidneys with severe stenosis than in those with no obvious obstruction, mild stenosis, or moderate stenosis (P < 0.05). Conclusion BOLD-MRI is an effective, noninvasive method for evaluating kidney oxygenation, which is important for proper treatment in RAS. It is sufficiently sensitive for detecting medulla ischemia and anoxia of the kidneys.

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Section: Discussionmentioning

confidence: 99%

Cortical and medullary oxygenation evaluation of kidneys with renal artery stenosis by BOLD-MRI

Zhao

Li²,

Meng

et al. 2022

PLoS ONE

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Meso-scale network analysis of resting state-fMRI brain network connectivity performs poorly as a prognostic tool in critically ill traumatic brain injury patients

Tjerkaski

Thompson

Bellander

et al. 2022

Neuroimage: Reports

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Mapping the orbitofrontal cortex using temporal fluctuations in cerebral blood flow

Abstract: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Cited by 2 publications

References 49 publications

Cortical and medullary oxygenation evaluation of kidneys with renal artery stenosis by BOLD-MRI

Cortical and medullary oxygenation evaluation of kidneys with renal artery stenosis by BOLD-MRI

Meso-scale network analysis of resting state-fMRI brain network connectivity performs poorly as a prognostic tool in critically ill traumatic brain injury patients

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