High utility itemset mining discovers itemsets whose utility is above a given threshold, where utilities measure the importance of itemsets. In high utility itemset mining, memory and time performance limitations cause scalability issues, when the dataset is very large. In this thesis, the problem is addressed by proposing a distributed parallel algorithm, PHUI-Miner, and a sampling strategy, which can be used either separately or simultaneously. PHUI-Miner parallelizes the state-of-theart high utility itemset mining algorithm HUI-Miner. The sampling strategy investigates the required sample size of a dataset, in order to achieve a given accuracy.We also propose an approach combining sampling with PHUI-Miner, which provides better time performance. In our experiments, we show that PHUI-Miner has high performance and outperforms the state-of-the-art non-parallel algorithm. The sampling strategy achieves accuracies much higher than the guarantee. Extensive experiments are also conducted to compare the time performance of PHUI-Miner with and without sampling.ii