2003
DOI: 10.1016/s0278-2391(03)00730-4
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Marginal and segmental mandibulectomy in patients with oral cancer: a statistical analysis of 106 cases

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Cited by 112 publications
(34 citation statements)
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“…Kawakita et al (8) conducted a retrospective cohort analysis of 222 patients with OSCC, in which they assessed the association between smoking status of patients and clinical outcome. Furthermore, Munoz Guerra et al (11) analyzed a 20-year cohort of 106 patients to assess the association between a worse prognosis and factors related to the surgical treatment of oral cancer.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Kawakita et al (8) conducted a retrospective cohort analysis of 222 patients with OSCC, in which they assessed the association between smoking status of patients and clinical outcome. Furthermore, Munoz Guerra et al (11) analyzed a 20-year cohort of 106 patients to assess the association between a worse prognosis and factors related to the surgical treatment of oral cancer.…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, the identification of factors associated with a poor prognosis has emerged as an important issue in the management of OSCC. Previous studies have evaluated various clinicopathological parameters as prognostic factors of OSCC, and the age (7) and smoking status (8) of patients, extracapsular spread in the cervical lymph nodes (9), TNM stage (5,10), status of the surgical resection margin, bone involvement and the size of the mandibulectomy (11), as well as the tumor size and microvascular invasion (12,13), have been shown to be independent prognostic factors in patients with OSCC. However, previous studies have assessed only few or groups of risk factors that might influence the prognosis, and the association between these factors and the prognosis of OSCC is inconsistent and complex.…”
Section: Introductionmentioning
confidence: 99%
“…Thus, the radiation treatment intended to prevent recurrence in cancer patients can lead to complications such as osteoradionecrosis [64], resulting in failure of the graft and revision surgeries [63]. Despite these aggressive therapies of large surgical margins and radiation, recent studies have reported recurrence rates varying between 13 – 34% after mandibulectomy, which underscores the need for new approaches for reducing tumor recurrence while improving healing [58, 60, 61, 65, 66]. …”
Section: Strategies For Healing Bone Damaged By Cancer-induced Diseasementioning
confidence: 99%
“…A marginal mandibulectomy is an oncologic procedure performed in conjunction with local soft‐tissue ablation that is performed when oral cancers approach or superficially involve the periosteum of the mandible. In the appropriately selected patients, it achieves excellent local control and survival rates 1. These composite resections of the anterior oral cavity resulting in variable loss of the ventral tongue, floor of mouth, and mandible have had a number of proposed reconstructive options.…”
Section: Introductionmentioning
confidence: 99%