Marginal Corneal Ulcers with Acute Beta Streptococcal Conjunctivitis and Chronic Dacryocystitis

Cohn, H; Mondino, Bartly J.; Brown, Stuart I.; Hall, Gregory D.

doi:10.1016/0002-9394(79)90246-0

Cited by 15 publications

(9 citation statements)

References 2 publications

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“…In our study, the corneal ulceration healed quickly after the treatment of the lacrimal drainage pathway disease in all cases, which is consistent with previous reports [ 3 , 4 , 6 ]. These results suggest that lacrimal drainage pathway disease is an essential factor for the development of corneal ulceration.…”

Section: Discussionsupporting

confidence: 93%

“…In this study, a culture of the corneal ulcer site was conducted in one case of lacrimal canaliculitis; however, the causative organism was not detected. Cohn et al reported one case of corneal ulcer associated with chronic dacryocystitis in which the bases of the ulcer were free of infiltrating, and bacteria were detected from the lacrimal sac but not from the peripheral corneal ulcers [ 3 ]. This is consistent with our review and is suggestive of the lack of infection at the cornea.…”

Section: Discussionmentioning

confidence: 99%

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Clinical characteristics of lacrimal drainage pathway disease-associated keratopathy

et al. 2022

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Purpose To report the clinical characteristics of 13 cases of noninfectious corneal ulceration related to lacrimal drainage pathway disease. Methods Medical records of 13 patients with lacrimal drainage pathway disease-associated keratopathy who were examined at Ehime University Hospital between April 2007 and December 2021 were analyzed. Results The predisposing lacrimal drainage pathway diseases for corneal ulceration were chronic dacryocystitis in seven patients and lacrimal canaliculitis in six patients. The corneal ulcers were located at the peripheral cornea in 10 patients and the paracentral cornea in three patients. All patients indicated few cellular infiltrations of the ulcerated area at the slit-lamp examination. Corneal perforation was found in seven patients. The primary identified organisms were Streptococcus spp. in chronic dacryocystitis and Actinomycetes spp. in lacrimal canaliculitis. All patients showed rapid healing of the epithelial defects after treatment of the lacrimal drainage pathway disease. The mean time elapsed between treatment of the lacrimal drainage pathway disease and re-epithelialization of corneal ulcer was 14.5 ± 4.8 days. Conclusion Lacrimal drainage pathway disease-associated keratopathy may be characterized by peripheral corneal ulcer with few cellular infiltrations, occasionally leading to corneal perforation. Treatment of the lacrimal drainage pathway disease could be the most effective treatment for lacrimal drainage pathway disease-associated keratopathy.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Clinical characteristics of lacrimal drainage pathway disease-associated keratopathy

et al. 2022

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“…[ 106 ] Also known as catarrhal infiltrates, marginal keratitis can occur secondary to the eyelid infection by other microorganisms, such as Hemophilus, Moraxella, or Streptococcus. [ 107 , 108 ]…”

Section: Introductionmentioning

confidence: 99%

Peripheral Ulcerative Keratitis: A Review

Hassanpour

ElSheikh

Arabi

et al. 2022

JOVR

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Peripheral ulcerative keratitis (PUK) is a rare but serious ocular condition that is an important clinical entity due to its ophthalmological and systemic implications. It is characterized by progressive peripheral corneal stromal thinning with an associated epithelial defect and can be associated with an underlying local or systemic pro-inflammatory condition, or present in an idiopathic form (Mooren ulcer). Associated conditions include autoimmune diseases, systemic and ocular infections, dermatologic diseases, and ocular surgery. Cell-mediated and autoantibody- mediated immune responses have been implicated in the pathogenesis of PUK, destroying peripheral corneal tissue via matrix metalloproteinases. Clinically, patients with PUK present with painful vision loss, a peripheral corneal ulcer, and often adjacent scleritis, episcleritis, iritis, or conjunctivitis. Diagnostic evaluation should be focused on identifying the underlying etiology and ruling out conditions that may mimic PUK, including marginal keratitis and Terrien marginal degeneration. Treatment should be focused on reducing local disease burden with topical lubrication, while simultaneously addressing the underlying cause with antimicrobials or anti-inflammatory when appropriate. Existing and emerging biologic immunomodulatory therapies have proven useful in PUK due to autoimmune conditions. Surgical treatment is generally reserved for cases of severe thinning or corneal perforation.

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“…e most common organisms causing IK are Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus pneumoniae, which are also present in the normal eye flora [12][13][14][15][16][17][18][19][20]. Post-LASIK keratitis reports have become increasingly common in recent years [21][22][23][24][25][26][27][28][29][30][31][32][33][34].…”

Section: Introductionmentioning

confidence: 99%

The Prevalence of Infectious Keratitis after Keratorefractive Surgery: A Systematic Review and Meta-Analysis Study

Afsharpaiman

Zare

Yasemi

et al. 2020

Journal of Ophthalmology

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Background. The keratorefractive surgeries (KRS) are one of the most common ocular surgeries. One of the dangerous complications of these surgeries is infectious keratitis (IK), which is the second cause of blindness after cataract surgery. The purpose of this study was to estimate the prevalence of IK after KRS in different parts of the world. Methods. In order to obtain relevant studies, all national and international databases including IranMedex, SID, Magiran, IranDoc, Medlib, ScienceDirect, PubMed, Scopus, Cochrane, Embase, Web of Science, and Google Scholar were searched using standard keywords. Results. IK prevalence after KRS was 0.000496% (0.000145% for the left eye and 0.000149% for the right eye). IK prevalence after KRS in the United States, Europe, and Asia was 0.000667%, 0.000473%, and 0.000045%, respectively, in all of which the common microorganisms were Staphylococci. Meta-regression showed no significant association between IK after KRS and either sample size or publication year of the studies. IK prevalence after KRS in the right eye was more than that in the left one. Also, the probability of IK incidence after LASIK surgery was more than PRK and LASEK. In the evaluation of continents, IK after KRS in the United States was more frequent compared with Europe and Asia. Conclusions. This study provided data as to the overall prevalence of IK following KRS and its variations according to the types of eye, surgery, pathogenic microorganism, and geographical location.

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Marginal Corneal Ulcers with Acute Beta Streptococcal Conjunctivitis and Chronic Dacryocystitis

Cited by 15 publications

References 2 publications

Clinical characteristics of lacrimal drainage pathway disease-associated keratopathy

Clinical characteristics of lacrimal drainage pathway disease-associated keratopathy

Peripheral Ulcerative Keratitis: A Review

The Prevalence of Infectious Keratitis after Keratorefractive Surgery: A Systematic Review and Meta-Analysis Study

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