“…However, gastrojejunal anastomoses are inherently ulcerogenic due to exposure of intestinal mucosa to gastric acid unopposed by pancreatic secretions. Marginal ulcers occur in up to 16 % of patients after Roux-en-Y gastrojejunostomy and may be associated with significant morbidity [ 5 ]. In addition, our patient had additional risk factors, including H. pylori colonization, smoking, malnutrition, and non-compliance with follow up which all contributed to development of a marginal ulcer and subsequent fistula.…”