Marijuana is both antiemetic and proemetic

Abstract

Although marijuana is sometimes used to treat chemotherapy-induced nausea and vomiting, when used long-term it can have a paradoxical hyperemetic effect known as cannabinoid hyperemesis syndrome. Knowledge of this phenomenon may reduce the ordering of unnecessary and expensive investigations, as well as inappropriate medical and surgical treatment in patients presenting with recurrent vomiting of unknown cause. This article reviews the pathophysiology, clinical presentation, diagnosis, and management of this emerging condition.

Maconha e gravidez: síndrome da hiperêmese por canabinoide - Relato de caso

“…A maconha é a terceira droga recreacional e a primeira ilícita mais consumida no mundo e no Brasil [1][2][3][4][5][6][7][8][9] , apresentando prevalência de 7,5% de uso na gravidez 8,10 .…”

“…Após a legalização da maconha e a permissão para seu uso medicinal e recreacional, seu consumo tem crescido nos Estados Unidos 2,7,11 . Esse crescimento traz novos quadros patológicos 9 , entre eles a síndrome da hiperêmese por canabinoide (SHC) 2,5,11 .…”

“…Desde o primeiro caso de SHC, relatado em 2004 na Austrália 5,12 , sua incidência aumentou no mundo 2,5,13 . Na literatura científica, foram encontrados 90 artigos no banco de dados PubMed, entre eles seis de pacientes grávidas.…”

“…A SHC surge em decorrência do consumo acentuado e crônico (pelo menos um ano) de maconha 2,6,8,11,13,14 e tem como sintoma característico a compulsão por banho quente 7 .…”

Cannabinoid Hyperemesis: An Erratic Syndrome Linked with Cannabis Abuse

“…The prevalence of use is higher in men than women, a gender gap that extended in the years 2007 to 2014 ( Figure 1) [7]. The number of people affected is not diaphanous as of 2015 [8]. Cannabis use is linked with copious acute and chronic adverse effects as stated earlier such as vomiting, followed by cyclic vomiting syndrome, intense feelings of nausea and accompanying symptoms, abdominal discomfort and compulsive hot bathing behaviour [3].…”