Marijuana Smoking in Men with HIV Infection: A Cause for Concern

Wenger, David; Crothers, Kristina

doi:10.1016/j.eclinm.2019.01.016

Cited by 4 publications

(1 citation statement)

References 10 publications

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“…The timing of illegal drug use was significantly more recent among individuals with HIV; 36% of respondents with HIV reported using any illegal drug in the past month compared to only 8.6% of the respondents without HIV/AIDS (p<0.0001) [4]. The percentage of males with HIV/AIDS who smoke marijuana daily has been on the rise since 1984 [160]. Marijuana use among PLWHA remained consistently higher after adjusting for demographic factors including age, sex, race/ethnicity, education, total family income (=$75,000), and marital status [4].…”

Section: Incidence Of Marijuana Use Amont Plwhamentioning

confidence: 98%

An update on drug–drug interactions between antiretroviral therapies and drugs of abuse in HIV systems

Desai

Burns

Gong

et al. 2020

Expert Opinion on Drug Metabolism & Toxicology

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Introduction: While considerable progress has been made in the fight against HIV/AIDS, to date there has not been a cure, and millions of people around the world are currently living with HIV/ AIDS. eople living with HIV/AIDS have substance abuse disorders at higher rates than noninfected individuals, which puts them at an increased risk of drug drug interactions.Areas covered: Potential drug drug interactions are reviewed for a variety of potential drugs of abuse, both licit and illicit. These drugs include alcohol, cigarettes or other nicotine delivery systems, methamphetamine, cocaine, opioids, and marijuana. Potential interactions include decreased adherence, modulation of drug transporters, or modulation of metabolic enzymes. We also review the relative incidence of the use of these drugs of abuse in People living with HIV/ AIDS.Expert opinion: Despite considerable improvements in outcomes, disparities in outcomes between PLWHA who use drugs of abuse, vs those who do not still exist. It is of critical necessity to improve outcomes in these patients, and to work with them to stop abusing drugs of abuse.

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Section: Incidence Of Marijuana Use Amont Plwhamentioning

confidence: 98%

An update on drug–drug interactions between antiretroviral therapies and drugs of abuse in HIV systems

Desai

Burns

Gong

et al. 2020

Expert Opinion on Drug Metabolism & Toxicology

View full text Add to dashboard Cite

show abstract

Changes in frequency of cannabis use among people with HIV during the COVID-19 pandemic: a multi-methods study to explore the underlying reasons for change

Parisi

Wang

Varma

et al. 2023

The American Journal of Drug and Alcohol Abuse

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Something to talk about; crosstalk disruption at the neurovascular unit during HIV infection of the CNS

Galpayage Dona,

Benmassaoud,

Gipson

et al. 2024

NeuroImmune Pharmacology and Therapeutics

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Although treatable with antiretroviral therapy, HIV infection persists in people living with HIV (PLWH). It is well known that the HIV virus finds refuge in places for which antiretroviral medications do not reach therapeutic levels, mainly the CNS. It is clear that as PLWH age, the likelihood of developing HIV-associated neurological deficits increases. At the biochemical level neurological dysfunction is the manifestation of altered cellular function and ineffective intercellular communication. In this review, we examine how intercellular signaling in the brain is disrupted in the context of HIV. Specifically, the concept of how the blood-brain barrier can be a convergence point for crosstalk, is explored. Crosstalk between the cells of the neurovascular unit (NVU) (endothelium, pericytes, astrocytes, microglia and neurons) is critical for maintaining proper brain function. In fact, the NVU allows for rapid matching of neuronal metabolic needs, regulation of blood-brain barrier (BBB) dynamics for nutrient transport and changes to the level of immunosurveillance. This review invites the reader to conceptually consider the BBB as a router or convergence point for NVU crosstalk, to facilitate a better understanding of the intricate signaling events that underpin the function of the NVU during HIV associated neuropathology.

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Marijuana Smoking in Men with HIV Infection: A Cause for Concern

Cited by 4 publications

References 10 publications

An update on drug–drug interactions between antiretroviral therapies and drugs of abuse in HIV systems

An update on drug–drug interactions between antiretroviral therapies and drugs of abuse in HIV systems

Changes in frequency of cannabis use among people with HIV during the COVID-19 pandemic: a multi-methods study to explore the underlying reasons for change

Something to talk about; crosstalk disruption at the neurovascular unit during HIV infection of the CNS

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