Marine-Derived Materials for the Development of Advanced Drug Delivery Systems

Ege, Hasan; Ege, Zeynep Ruya; Gunduz, Oguzhan

doi:10.1007/978-3-031-56363-8_55

Handbook of the Extracellular Matrix 2024

DOI: 10.1007/978-3-031-56363-8_55

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Marine-Derived Materials for the Development of Advanced Drug Delivery Systems

Hasan Ege,

Zeynep Ruya Ege,

Oguzhan Gunduz

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2024

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Cited by 1 publication

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Oceanic Breakthroughs: Marine-Derived Innovations in Vaccination, Therapy, and Immune Health

Gamberi,

Leverette,

Davis

et al. 2024

Vaccines

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The vast, untapped potential of the world’s oceans is revealing groundbreaking advancements in human health and vaccination. Microalgae such as Nannochloropsis spp. and Dunaliella salina are emerging as resources for recombinant vaccine development with specific and heterologous genetic tools used to boost production of functional recombinant antigens in Dunaliella salina and Nannochloropsis spp. to induce immunoprotection. In humans, several antigens produced in microalgae have shown potential in combating diseases caused by the human papillomavirus, human immunodeficiency virus, hepatitis B virus, influenza virus, Zika virus, Zaire Ebola virus, Plasmodium falciparum, and Staphylococcus aureus. For animals, microalgae-derived vaccine prototypes have been developed to fight against the foot-and-mouth disease virus, classical swine fever virus, vibriosis, white spot syndrome virus, and Histophilus somni. Marine organisms offer unique advantages, including the ability to express complex antigens and sustainable production. Additionally, the oceans provide an array of bioactive compounds that serve as therapeutics, potent adjuvants, delivery systems, and immunomodulatory agents. These innovations from the sea not only enhance vaccine efficacy but also contribute to broader immunological and general health. This review explores the transformative role of marine-derived substances in modern medicine, emphasizing their importance in the ongoing battle against infectious diseases.

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Oceanic Breakthroughs: Marine-Derived Innovations in Vaccination, Therapy, and Immune Health

Gamberi,

Leverette,

Davis

et al. 2024

Vaccines

View full text Add to dashboard Cite

show abstract

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Marine-Derived Materials for the Development of Advanced Drug Delivery Systems

Cited by 1 publication

References 74 publications

Oceanic Breakthroughs: Marine-Derived Innovations in Vaccination, Therapy, and Immune Health

Oceanic Breakthroughs: Marine-Derived Innovations in Vaccination, Therapy, and Immune Health

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