With the development of science and technology, the ocean is providing a strong material and economic guarantee for the development of human society. The issue of assessing the health of the marine ecosystem and providing data support for the healthy development of the marine system has become a hot topic for many scholars. This study mainly establishes a marine ecosystem health assessment system, analyzes the health degree of marine ecosystems using information entropy, and then adopts the gray correlation method and the DPSIR model to predict the health level of marine ecosystems, discusses the sustainability of the marine generating system, and provides a development direction for the healthy development of marine ecology. The entropy of the “supportive input” criterion layer is the highest, accounting for 42.25%. From the analysis of the comprehensive health index from 2020 to 2023, the IHI ranges from 0.6 to 1.5, and the state of the ocean can reach a healthy level in the future period, which shows that the development of the economy and science and technology influences the healthy development of marine ecology.