Monkeypox is an uncommon virus that is mostly found in Central and West Africa and can be transmitted to humans from animals. The treatment of monkeypox requires the prompt isolation of potential cases, strict infection prevention protocols for healthcare workers, and placing close contacts under quarantine. It is essential to have surveillance systems in place to monitor the spread, while public health education is crucial in order to increase awareness and encourage the adoption of preventative measures. While there is no targeted antiviral treatment, smallpox vaccination has proven to be effective in preventing the disease, and scientists are currently working on developing vaccines specifically for monkeypox. Control tactics concentrate on identifying and controlling animal reservoirs, imposing travel limitations, and managing possible vectors. It is crucial to make efforts to minimize the interaction between humans and animals in areas where diseases are prevalent. Supportive care is the main component of treatment, focused on easing symptoms, addressing secondary bacterial infections with antibiotics, managing pain, and maintaining fluid levels. It is crucial for local health authorities to work together with international organizations in order to effectively implement control measures and prevent outbreaks. As our understanding of monkeypox grows ongoing research and monitoring play a key role in improving methods for managing, controlling, and treating the disease. This highlights the necessity of a comprehensive and well-coordinated approach to addressing this public health issue.