Marine polysaccharides: Biological activities and applications in drug delivery systems

Geng, Hongxu; Chen, Meijun; Guo, Chunjing; Wang, Wenxin; Chen, Daquan

doi:10.1016/j.carres.2024.109071

Carbohydrate Research

2024

DOI: 10.1016/j.carres.2024.109071

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Marine polysaccharides: Biological activities and applications in drug delivery systems

Hongxu Geng,

Meijun Chen,

Chunjing Guo

et al.

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Cited by 5 publications

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Advances in polysaccharide‐based materials for biomedical and pharmaceutical applications: A comprehensive review

Li,

Ahmed,

Hussein

et al. 2024

Archiv der Pharmazie

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Polysaccharides, the most abundant biopolymers in nature, have attracted the attention of researchers and clinicians due to its practicality in biomedical and pharmaceutical sciences. These biomaterials have high bioavailability and play structural and functional roles in living organisms. Polysaccharides are classified into several groups based on their origin, including plant polysaccharides and marine polysaccharides (like chitosan, hyaluronic acid, dextran, alginates, etc.) with specific applications. These biopolymers possess unique physicochemical (such as surface functional groups, solubility, and stability), mechanical (like mechanical strength and tensile), and biomedical (such as antioxidant activity, biocompatibility, biodegradability, renewability, and non‐immunogenicity) characteristics which have made them excellent platforms for a wide variety of biomedical and pharmaceutical applications. Ease of extraction and different preparation approaches are mentioned as other potential properties of polysaccharides that further improved their practicality in biomedical sciences. They have high drug/bioactive encapsulation capacity and sustained/controlled release manner in in vivo microenvironments. The anti‐inflammatory and immunomodulation, stimuli‐responsive drug/bioactive release, and passive and active drug/bioactive delivery are considered the potential features of these biopolymers in pharmaceutical sciences. Polysaccharides have indicated practical applications in biomedical sciences, including biosensors, tissue engineering, implantation, wound healing, vascular grafting, and vaccines. This review highlights the advances of polysaccharide‐based materials in biomedical and pharmaceutical sciences.

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Advances in polysaccharide‐based materials for biomedical and pharmaceutical applications: A comprehensive review

Li,

Ahmed,

Hussein

et al. 2024

Archiv der Pharmazie

View full text Add to dashboard Cite

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International Journal of Biological Macromolecules

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Development of pH-sensitive chitosan/plant extract microcapsules: Enhanced corrosion protection for carbon steel in HCl solution

Wang,

Sun,

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Marine polysaccharides: Biological activities and applications in drug delivery systems

Cited by 5 publications

References 276 publications

Advances in polysaccharide‐based materials for biomedical and pharmaceutical applications: A comprehensive review

Advances in polysaccharide‐based materials for biomedical and pharmaceutical applications: A comprehensive review

Roles and mechanisms of fucoidan against dermatitis: A review

Development of pH-sensitive chitosan/plant extract microcapsules: Enhanced corrosion protection for carbon steel in HCl solution

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