Marjolin ulcer: a case report

Ortíz, Beatriz Di Martino; Riveros, Rosalba; Gabriela, Martinez Braga; Sosa, Raquel Medina de; Masi, Mirtha Rodríguez; Knopfelmacher, Oilda; Lezcano, Lourdes Bolla de

doi:10.7241/ourd.20141.12

Cited by 5 publications

(12 citation statements)

References 6 publications

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“…Since then many reports have been published, and today it is well accepted that Marjolin's ulcer describes malignant degeneration in burn scars, chronic venous insufficiency ulcers, pressure ulcers, vaccination sites, urinary fistulas, frostbite, snakebites, osteomyelitis, pilonidal abscesses, hydradenitis suppurativa, herpes zoster, grating areas, dog bites, knife wounds, gunshot wounds, post-traumatic chronic wounds and skin injuries caused by chronic exposure to heat: erythema ab igne (1,3).…”

Section: Letter To the Editormentioning

confidence: 99%

“…Malignant changes in scars can be observed at any age, but the average age at the time of diagnosis is highly variable depending on the study: in general over 50 years (1,3,4).…”

Section: Letter To the Editormentioning

confidence: 99%

“…The gender distribution (male to female ratio) ranges from 3:1 to 2:1, and basal cell carcinomas have been more frequently reported in males and melanoma in females (1,5).…”

Section: Letter To the Editormentioning

confidence: 99%

“…Degeneration of scars is well known from ancient times; in the first century AD, Aurelius Cornelius Celsus described cancer in chronic ulcers for the first time (1).…”

mentioning

confidence: 99%

“…Many centuries after Celsus, in 1828, Jean-Nicolas Marjolin from Paris University, published a half-page article in Dictionnaire de Medicine, with a clear description of four cases of specific ulceration, named 'ulcère verruqueux' ('verucous ulcer'). Although he did not mention the malignancy of the ulcerations and also did not make any correlation with pre-existing scars or chronic ulcers, since then the terminology of 'Marjolin's ulcer' has been accepted even till today (1,2).…”

mentioning

confidence: 99%

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Malignant degeneration of scars in elderly people (Marjolin's ulcers)

Brzeziński¹,

Solovan

Chiriac

2015

International Wound Journal

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Section: Letter To the Editormentioning

confidence: 99%

“…Malignant changes in scars can be observed at any age, but the average age at the time of diagnosis is highly variable depending on the study: in general over 50 years (1,3,4).…”

Section: Letter To the Editormentioning

confidence: 99%

“…The gender distribution (male to female ratio) ranges from 3:1 to 2:1, and basal cell carcinomas have been more frequently reported in males and melanoma in females (1,5).…”

Section: Letter To the Editormentioning

confidence: 99%

“…Degeneration of scars is well known from ancient times; in the first century AD, Aurelius Cornelius Celsus described cancer in chronic ulcers for the first time (1).…”

mentioning

confidence: 99%

mentioning

confidence: 99%

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Malignant degeneration of scars in elderly people (Marjolin's ulcers)

Brzeziński¹,

Solovan

Chiriac

2015

International Wound Journal

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Marjolins Ulcer: Clinicopathological Profile and Treatment Patterns

Kumar,

Narayanan,

Ganesh

et al. 2023

J. Anal. Oncol.

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Purpose: Marjolins ulcer is a malignant transformation arising from chronic ulcers or previously traumatized scars that occur usually after burns. This article aims to study the clinicopathological profile and treatment patterns of Marjolins ulcer. Materials and Methods: Retrospective analysis of all Marjolins ulcer patients presented to Vydehi Cancer Centre from 2018 to 2021 was done. A total of 27 patients of all age groups were included in the study. All information regarding detailed history, clinical examination, treatment details were retrospectively collected and analysed. Results: Most of the patients were in the 5th decade of life with an overall male preponderance. The most common cause for Marjolins ulcer was Burns scars followed by Trauma. Lower extremities were found to be the most predominant site. The mean latency period for the development of Marjolins ulcer was 11 years. Squamous cell carcinoma was the most common histological subtype, Adjuvant Radiotherapy was given to the patients with high-risk features. Conclusion: Chronic non-healing ulcers that do not respond to treatment should be carefully examined for malignant transformation. Surgery is the mainstay of treatment and Adjuvant Radiotherapy should be considered in high-risk cases to reduce locoregional recurrence.

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Twenty-Seven Cases of Marjolins Ulcer; An Institutional Experience on Diagnosis, Treatment and Outcomes

BR,

Shankar,

Narayanan

et al. 2024

Asian Pac J Cancer Biol

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Purpose: Marjolins ulcer is a malignant transformation that arises from chronic ulcers or previously traumatized scar that occur usually after burns. To study the clinicopathological characteristics and treatment outcomes of Marjolins ulcer at our institute. Materials and methods: Retrospective analysis of all Marjolins ulcer patients presented to our department from 2018 to 2021 was done. A total of 27 patients of all age groups were included in the study. All the information regarding the diagnosis, treatment and outcome details were collected and analysed.Results: Most of the patients were in the 5th decade of life with an overall male preponderance. The most common cause for Marjolin ulcer was Burns Scar. The mean latency period for the development of Marjolins ulcer was 11 years. Squamous cell carcinoma was the most common histological subtype. 18.5% patients received Adjuvant radiotherapy. At the median follow up of 14 months, one patient presented with locoregional relapse.Conclusion: Chronic non-ulcers that do not respond to treatment should be carefully examined by multidisciplinary team for malignant transformation. Surgery is the mainstay of treatment and Adjuvant Radiotherapy should be considered in high-risk cases to reduce locoregional recurrence. Tumour size and nodal involvement are the main predictors of locoregional relapse.

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Marjolin ulcer: a case report

Cited by 5 publications

References 6 publications

Malignant degeneration of scars in elderly people (Marjolin's ulcers)

Malignant degeneration of scars in elderly people (Marjolin's ulcers)

Marjolins Ulcer: Clinicopathological Profile and Treatment Patterns

Twenty-Seven Cases of Marjolins Ulcer; An Institutional Experience on Diagnosis, Treatment and Outcomes

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