Wheat accessions were genotyped with molecular markers linked to wheat leaf rust resistance genes Lr9, Lr10, Lr19, Lr24, Lr26, Lr34, and Lr37. They included 1920 wheat plants and 46 commercial varieties bred at the Lukyanenko Institute. Basically, the analyzed varieties had the inefficient gene Lr10, poorly efficient Lr26 and Lr34, or their combinations. The highly efficient genes Lr9 and Lr24 were not detected. The Lr19 gene, effective in the Krasnodar region, was identified in varieties Pallada and Yara. The resistance gene Lr37 was found in the Morozko variety. Within a short time, the F 2 and F 3 plants with the introgression of genes Lr9, Lr19, Lr24, and Lr37 were obtained. Accessions with combinations Lr24 +Lr37, Lr24 + Lr19, Lr24 + Lr9, Lr19 + Lr37, Lr37 + Lr9, and Lr19 + Lr9 were identified. Seven plants with the combination of three genes Lr37 + Lr19 + Lr9 and one with Lr37 + Lr24 + Lr9 were selected.