Markers of lipid metabolism and antioxidant system of organisms of cows depending on their physiological state

Baimishev, Murat; Yeremin, S.; Plemyashov, Kirill; Baimishev, Hamidulla; Konopeltsev, I.G.

doi:10.1088/1755-1315/403/1/012013

Cited by 5 publications

(3 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…B., Da Y., VanRaden P. M. Symposium review: Genetics, genome wide association study, and genetic improvement of dairy fertility traits // Journal Dairy Science. 2019 parameters. Methods.…”

Section: обсуждение и выводы (Discussion and Conclusion)mentioning

confidence: 99%

Postpartum blood biochemical profile in heifers in connection with polymorphic variants of the SCD1 gene and reproductive ability

Leibova¹,

Pozovnikova²

2020

Agrarian Bulletin of The

View full text Add to dashboard Cite

Abstract. The purpose of this study was to compare the biochemical profile of blood in the first two months of lactation in first-calf cows with polymorphic variants of the stearoyl-CoA-desaturase gene (SCD1) and its relationship with reproductive parameters. Methods. The work was carried out in one of the breeding factories of the Leningrad Region on first-calf cows of the Holstein breed with an average milk yield of 9073 ± 263 kg for 305 days of lactation. Animal genotypes were determined by PCR-RFLP. Serum samples were used to determine the content of total protein, albumin, urea, glucose, triglycerides, cholesterol, the activity of the enzymes AST (aspartate aminotransferase), ALT (alanine aminotransferase), alkaline phosphatase (alkaline phosphatase), GGT (γ-glutamyl transferase). Laboratory studies of blood serum were performed on a RX Daytona biochemical analyzer (Randox Laboratories, UK) using reagents from Cormay, Poland. The results of the study. Of the 20 individuals, 12 animals were carriers of the CT genotype, the remaining first-calf cows had the CC (n = 6) and TT (n = 2) genotypes. Blood biochemical parameters were determined in animals with CT and SS genotypes. On the 44-50th day of lactation in animals with CT genotype, the urea concentration and AST activity decreased by 1.2–1.3 times (p ≤ 0.001). In individuals with the SS genotype, no change in these indicators was found. As a result, at the end of the second month of lactation in cows with the SS genotype, blood urea and AST activity were 1.2 times higher than in animals with the CT genotype. The content of total cholesterol increased 1.3–1.4 times (p < 0.01) by the 6–7th week of lactation in cows of both genotypes (SS and CT). The remaining biochemical parameters did not differ between time intervals within the same genotype, and between groups of animals with different genotypes. When distributing the examined cows into groups depending on the genotype and service period, it was found that the duration of the service period of more than 150 days is twice as common in individuals with the CC genotype. In cows with the heterozygous ST genotype of the SCD1 gene, biochemical profile indicators are more optimal, which may be associated with an increased frequency of occurrence of individuals with a shorter service period.

show abstract

“…B., Da Y., VanRaden P. M. Symposium review: Genetics, genome wide association study, and genetic improvement of dairy fertility traits // Journal Dairy Science. 2019 parameters. Methods.…”

Section: обсуждение и выводы (Discussion and Conclusion)mentioning

confidence: 99%

Postpartum blood biochemical profile in heifers in connection with polymorphic variants of the SCD1 gene and reproductive ability

Leibova¹,

Pozovnikova²

2020

Agrarian Bulletin of The

View full text Add to dashboard Cite

show abstract

“…Генетически обусловленный потенциал маточного поголовья требует соответствий условий кормления и содержания, а так же максимальной активизации обменных процессов в организме [7,9]. В первую очередь, интенсивный лактогенез ассоциирован с высокой потребностью животного в энергии, дефицит которой негативно сказывается на процессах метаболизма и зачастую может стать причиной развития различных патологий, снижения воспроизводительной способности и молочной продуктивности [1,6].…”

Section: введение / Introductionunclassified

The effect of the concentration of β-hydroxybutyrate and glucose in the blood on the reproductive function and milk productivity of cows

Nikolaev

2023

jour

View full text Add to dashboard Cite

The intensity of metabolic processes in highly productive cows is associated with metabolic disorders and the development of dystrophic changes in the body. The paper evaluates the effect of the concentration of β-hydroxybutyrate and glucose in the blood of new-bodied cows on the indicators of reproductive ability and milk productivity. To do this, venous blood was obtained from cows of different ages after childbirth, where the concentration of glucose and β-hydroxybutyrate was determined. Depending on the level of glucose and ketone bodies, animals were retrospectively differentiated into groups and the severity of economically useful signs was determined. It was found that cows with a glucose level above 3.3 mmol/l required 0.6 more inseminations (P≤0.01), compared with animals whose indicators were in the range of 2.2...3.3 mmol/l. At the same time, the greatest difference in the multiplicity of insemination was present in animals 3...7 lactation (1.2 inseminations per fertilization; P≤0.001). The period from calving to fertilization in cows with a high glucose content was longer by 39.4 days (P < 0.05), while the maximum deviation was found among animals older than the 2nd lactation (by 43.4%; P< 0.05). An increase in the level of β-hydroxybutyrate over 0.7 mmol/l was also accompanied by a deterioration in reproductive function. Thus, the lengthening of the infertility period for all lactation was 21.2 days (P≤0.05). The most pronounced negative effect on reproductive function in ketonemia was observed in first-heifers and cows of the second lactation. So, after the first birth, the lengthening of the period from calving to fertilization was 42.0 days (P < 0.05), and after the second lactation - 29.2 days (P < 0.05). Thus, an increase in the level of glucose and β-hydroxybutyrate in the blood negatively affects, first of all, the reproductive function of cows, and to a lesser extent, the indicators of milk productivity.

show abstract

“…Классически к данной группе относят маркеры биохимического состава крови. Стоит отметить, что биохимический профиль крови во многом зависит от физиологического состояния животного, границы вариабельности которого детерминированы генетическим материалом [7,8]. Тем не менее изменчивость ее состава также обусловлена внешними факторами среды, что отображает адаптационно-метаболическое состояние организма [9].…”

unclassified

The use of biochemical blood markers for early prediction of the intensity of live weight gain of calves

Nikolaev

2022

Аграрная наука Евро-Северо-Востока

View full text Add to dashboard Cite

The aim of the research was to identify promising biochemical markers of blood associated with the intensity of live weight gain in young cattle. The work was carried out in 2021...2022 in the conditions of the dairy farm of LLC Severnaya Niva in the Kortkerossky district of the Komi Republic. A group of newborn heifers of the Kholmogorsky breed (n = 30) was selected for the experiment. It has been established that on the first day after birth, calves with intensive growth rates had lower AsAT activity (r = -0.510) and iron concentration (r = -0.650) in blood serum, and vice versa a higher level of SMLMM рlasma (0.626). At later stages of the analysis, a pronounced correlation of the intensity of body weight gain was observed with respect to the activity of alkaline phosphatase: -0.639 and -0.744 on day 7 and 14, respectively. It was determined that many of the calculated coefficients obtained during the blood test on the 14th day after birth had a more noticeable correlation with the intensity of growth. Such markers included: Alkaline phosphatase/Calcium (-0.746), Alkaline phosphatase/Magnesium (-0.756), Magnesium/Alkaline Phosphatase (-0.760), Calcium×Phosphorus/Alkaline Phosphatase (0.758) and Alkaline Phosphatase/(Calcium+Magnesium) (-0.753). At the next stage, the analysis of the rate of live weight gain in heifers ranked by the increase in the values of the developed coefficients was carried out. It is proved that the use of coefficients contributed to a more pronounced differentiation of the rate of weight gain in comparison with the values established with the use of one alkaline phosphatase. Thus, the calculated index of Alkaline phosphatase/Calcium/ Magnesium on the 1st, 7th and 14th days of postnatal ontogenesis provided a difference between the phenotypes of the 1st and 3rd groups by 74.1(P≤0.05), 92.6 (P≤0.01) and 90.7 (P≤0.001) g of weight gain per day, whereas the difference when using one alkaline phosphatase was 33.3; 16.0 and 12.2 % less. Thus, the use of these coefficients to predict the rate of live weight gain in calves can increase the accuracy of the selection of animals with the desired phenotype in early postnatal ontogenesis.

show abstract

Markers of lipid metabolism and antioxidant system of organisms of cows depending on their physiological state

Cited by 5 publications

References 8 publications

Postpartum blood biochemical profile in heifers in connection with polymorphic variants of the SCD1 gene and reproductive ability

Postpartum blood biochemical profile in heifers in connection with polymorphic variants of the SCD1 gene and reproductive ability

The effect of the concentration of β-hydroxybutyrate and glucose in the blood on the reproductive function and milk productivity of cows

The use of biochemical blood markers for early prediction of the intensity of live weight gain of calves

Contact Info

Product

Resources

About