Markers shaping the future of preventive dentistry

Abstract

Detecting pathologies at their earliest stages can signifi cantly aff ect patient discomfort, prognosis, therapeutic intervention, survival rates, and recurrence. The use of tissue biomarkers in basic and clinical research and even in clinical practice not only became very common but also their presence as primary endpoints in clinical trials are now very well accepted. The use of tissue biomarkers, and mainly laboratory-measured biomarkers, in clinical set up is somewhat newer, and the suitable approaches to this practice are still in the process of development and refi nement. This review highlights contemporary innovations and explores recent discoveries about markers in lesions of oral cavity.